Sesamin alleviates diabetes-associated behavioral deficits in rats: The role of inflammatory and neurotrophic factors

S Ghaderi, M Rashno, A Nesari, SE Khoshnam… - International …, 2021 - Elsevier
… were assessed in the cerebral cortex and hippocampal … to over-activation of poly-(ADP-ribose)-polymerase
(PARP). In turn, … of Ses against diabetes-induced neuronal loss seems to be …

Salvia miltiorrhiza in diabetes: A review of its pharmacology, phytochemistry, and safety

Q Jia, R Zhu, Y Tian, B Chen, R Li, L Li, L Wang, Y Che… - Phytomedicine, 2019 - Elsevier
… In order to fully understanding of the roles of SM in diabetes, we here review its phytochemistry,
and diabetic improving activities as well as toxicity. Firstly, we briefly summarized the …

[HTML][HTML] Aqueous Ajwa dates seeds extract improves memory impairment in type-2 diabetes mellitus rats by reducing blood glucose levels and enhancing brain …

V Mani, M Arfeen, S Sajid, Y Almogbel - Saudi Journal of Biological …, 2022 - Elsevier
… normal as well as in diabetes-induced models. Reference to … enhancing the action of
poly(ADP-ribose) polymerase (PARP-1… importance of insulin and its receptors, found in the …

[PDF][PDF] Role of phytotherapy in diabetic neuropathy and neurodegeneration: from pathogenesis to treatment

ND Solanki, SK Bhavsar, DT Pandya - J Phytopharmacol, 2018 - phytopharmajournal.com
… Even in the absence of overt cerebrovascular accidents or … leads to activation of the Poly
[ADP-ribose] polymerase [PARP] … early diabetesinduced changes in peripheral nerve function, …

Edaravone abrogates LPS-induced behavioral anomalies, neuroinflammation and PARP-1

CS Sriram, A Jangra, SS Gurjar, P Mohan… - Physiology & …, 2016 - Elsevier
… inflammation could be an exciting approach to deal with mood disorders [49]. Poly(ADP-ribose)
polymerase-1 (PARP-1) is an enzyme catalyzes poly(ADP-ribosyl)ation (PARylation), a …

[HTML][HTML] Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions

N Apostolova, F Iannantuoni, A Gruevska, J Muntane… - Redox biology, 2020 - Elsevier
… In line with this, one report demonstrated that metformin exerts its protective cardiovascular
effect by reducing the activity of poly (ADP-ribose) polymerase 1 (PARP1) via the AMPK-…

Diabetic Neuropathy and Neuroprotection by Natural Products

N Solanki, H Koria - Indopathy for Neuroprotection: Recent …, 2022 - books.google.com
… the cell activates the Poly (ADP-ribose) polymerase (PARP) … dysfunction [41]. Each of these
mechanisms and the central … and Aβ deposition Attenuated diabetesinduced mechanical …

Effect of natural products on diabetes associated neurological disorders

SS Patel, M Udayabanu - Reviews in the Neurosciences, 2017 - degruyter.com
… attenuated cerebral infract size as well as reduced memory and motor impairment in ischemia…
granatum treatment restored diabetes induced increase in lipid peroxidation and decrease …

The role of HIF1α-PFKFB3 pathway in diabetic retinopathy

J Min, T Zeng, M Roux, D Lazar, L Chen… - The Journal of …, 2021 - academic.oup.com
… ADP)ribosylation of the enzyme in poly(ADP-ribose) polymerase (PARP)-dependent fashion
… have been found to be protected from diabetes-induced oxidative stress (75). Accumulation …

Targeting high glucose-induced epigenetic modifications at cardiac level: the role of SGLT2 and SGLT2 inhibitors

L Scisciola, F Taktaz, RA Fontanella… - Cardiovascular …, 2023 - Springer
… In a zebrafish model of diabetes induced by streptozotocin injection, hyperglycemia induced
a 5–tenfold increase in RNA expression of TETs through poly (ADP-ribose) polymerases (…