Pharmacokinetics and toxicokinetics roles of membrane transporters at kidney level

J Veiga-Matos, F Remião… - Journal of Pharmacy & …, 2020 - journals.library.ualberta.ca
… the organism from the moment it is absorbed until it is excreted. … In addition, we will also
describe the different xenobiotics … in the absorption, distribution and elimination of xenobiotics. …

Absorption, distribution, metabolism, excretion and toxicity of microplastics in the human body and health implications

P Wu, S Lin, G Cao, J Wu, H Jin, C Wang… - Journal of Hazardous …, 2022 - Elsevier
… ranges from 0.9 × 10 4 to 7.9 × 10 4 items per year. The intake of MPs would be further
distributed in different tissues and organs of humans depending on their sizes. The excretion has …

Plant pharmacology: Insights into in-planta kinetic and dynamic processes of xenobiotics

T Malchi, S Eyal, H Czosnek, M Shenker… - Critical Reviews in …, 2022 - Taylor & Francis
… to drugs in terms of drug absorption, distribution, metabolism and elimination (ADME). …
results of plant xenobiotic accumulation that enables comparison between methods, plants …

Absorption, distribution, metabolism and excretion of the biomaterials used in Nanocarrier drug delivery systems

C Su, Y Liu, R Li, W Wu, JP Fawcett, J Gu - Advanced drug delivery reviews, 2019 - Elsevier
… EPR effects and promote uptake of drug by cancer cell lines. As xenobiotics, MDNS can …
182]; Mice [182] PVA absorption into the blood from different injection sites decreased in the …

Metabolism, pharmacokinetics and excretion of [14C]dimethyl fumarate in healthy volunteers: an example of xenobiotic biotransformation following endogenous …

L Xu, CC Peng, K Dawson, S Stecher, J Woodworth… - Xenobiotica, 2023 - Taylor & Francis
… adducts showed that the mass differences between y’7 and y’… [ 14 C]DMF is well absorbed
and extensively metabolised via the … or species differences in the metabolism and excretion of …

[HTML][HTML] Current trends in drug metabolism and pharmacokinetics

Y Li, Q Meng, M Yang, D Liu, X Hou, L Tang… - … Pharmaceutica Sinica B, 2019 - Elsevier
xenobiotic metabolic pathways and the involvement of novel … of drug absorption, distribution,
metabolism, and excretion (… Total CYP concentrations are significantly different between

The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions

D Kovacsics, I Patik… - … on drug metabolism & …, 2017 - Taylor & Francis
… studies do not necessarily distinguish between a transported substrate and an inhibitor. …
bilirubin, and xenobiotic reabsorption [Citation11]. The key role of OATP1B1 in hepatic drug …

Quantification of proteins involved in intestinal epithelial handling of xenobiotics

ZM Al‐Majdoub, N Couto, B Achour… - Clinical …, 2021 - Wiley Online Library
… poorly predictive of human intestinal metabolism; 2 the nature, … appear to be significantly
different from those in experimental … to absorption, distribution, metabolism and excretion can …

Pharmacomicrobiomics: Influence of gut microbiota on drug and xenobiotic metabolism

IJ Dikeocha, AM Al‐Kabsi, M Miftahussurur… - The FASEB …, 2022 - Wiley Online Library
… of xenobiotics from pollution, manufacturing processes or from the … In this review, we discussed
different mechanisms of drug– gut … compounds followed by conjugation and excretion.If …

Cytochrome P450 enzymes, drug transporters and their role in pharmacokinetic drug-drug interactions of xenobiotics: a comprehensive review

S Maddi, T Goud, P Srivastava, E Ilhan… - Open Journal of …, 2017 - chemisgroup.us
… in drug absorption, distribution, metabolism or excretion, … conjugates between glutathione
and reactive xenobiotics by … In SLCO gene, a lot of sequence variations like single nucleotide …