The distribution, metabolism, and excretion of trichothecene mycotoxins
SP Swanson, RA Corley - … Mycotoxicosis Pathophysiologic Effects …, 2017 - taylorfrancis.com
… variations in xenobiotic metabolism have been documented. Major differences may result
from … have occurred from rapid absorption and distribution of the toxin from the gastrointestinal …
from … have occurred from rapid absorption and distribution of the toxin from the gastrointestinal …
Gills as a glutathione-dependent metabolic barrier in Pacific oysters Crassostrea gigas: Absorption, metabolism and excretion of a model electrophile
… for phase II xenobiotic metabolism and excretion in bivalves. … Thus, it is essential to
characterize how different organs … The data from this study reinforce the idea of a central role of …
characterize how different organs … The data from this study reinforce the idea of a central role of …
Absorption, distribution, metabolism and excretion (ADME) of the ALK inhibitor alectinib: results from an absolute bioavailability and mass balance study in healthy …
PN Morcos, L Yu, K Bogman, M Sato, H Katsuki… - Xenobiotica, 2017 - Taylor & Francis
… from this study and allow for a comprehensive understanding of the absorption, distribution,
… The difference between 84% of the parent eliminated and 75% of unabsorbed dose is 9%, …
… The difference between 84% of the parent eliminated and 75% of unabsorbed dose is 9%, …
Disposition and Fate of Toxicants
PK Gupta, PK Gupta - Concepts and Applications in Veterinary Toxicology …, 2019 - Springer
… absorption, distribution, metabolism/biotransformation, and excretion (ADME) of xenobiotics
… Significant differences in metabolic mechanisms exist between species. For example, …
… Significant differences in metabolic mechanisms exist between species. For example, …
Absorption, distribution, metabolism, and excretion of [14C]‐dasotraline in humans
YL Chen, E Skende, J Lin, Y Yi… - Pharmacology …, 2017 - Wiley Online Library
… absorbed, and extensively metabolized by oxidation and subsequent phase II conjugations.
The findings from this study also demonstrated that metabolism … difference in elimination t 1/…
The findings from this study also demonstrated that metabolism … difference in elimination t 1/…
Specific features of pharmacokinetics in children
P Matalová, K Urbánek… - Drug metabolism reviews, 2016 - Taylor & Francis
… drugs and other xenobiotics from cells under physiological as … differences were observed
among the age categories from 7 … route of metabolism and excretion of the drug, its distribution …
among the age categories from 7 … route of metabolism and excretion of the drug, its distribution …
[PDF][PDF] Drug biotransformation
MA Correia - Basic & clinical pharmacology, 2018 - academia.edu
… compounds called xenobiotics—substances absorbed across the … different patients because
of individual differences in drug distribution and rates of drug metabolism and elimination…
of individual differences in drug distribution and rates of drug metabolism and elimination…
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans
P Schlosser, Y Li, P Sekula, J Raffler… - Nature …, 2020 - nature.com
… from continuous systemic processes related to the absorption… of 1,172 endogenous and
xenobiotic metabolites, replicate … differences, but our current study cannot distinguish between …
xenobiotic metabolites, replicate … differences, but our current study cannot distinguish between …
Effects of Xenobiotics on Nutrition
P Xu - Nutritional Toxicology, 2022 - Springer
… affect each other from the steps of digestion, absorption, metabolism, and excretion. Here,
we … of toxicants on nutrients takes place at different stages, including absorption, distribution, …
we … of toxicants on nutrients takes place at different stages, including absorption, distribution, …
Biotransformation of xenobiotics in living systems—metabolism of drugs: Partnership of liver and gut microflora
… of a xenobiotic from those favoring absorption (lipophilicity) … Potential impacts of species
differences in drug metabolism … Finally, the conjugated xenobiotics are being excreted out by …
differences in drug metabolism … Finally, the conjugated xenobiotics are being excreted out by …