Control of dendritic spine morphological and functional plasticity by small GTPases

KM Woolfrey, DP Srivastava - Neural plasticity, 2016 - Wiley Online Library
neuron’s axon is much thinner than the dendrite … in hippocampal neurons [65]. Interestingly,
the spatiotemporal dynamics of Ras activation was again different to that of the Rho GTPases

Rab GTPase signaling in neurite outgrowth and axon specification

D Villarroel‐Campos, FC Bronfman… - …, 2016 - Wiley Online Library
… In cultured hippocampal neurons, for example, axon determination during neuronal
polarization is preceded by bulk cytoplasmic flow and polarized trans-Golgi network (TGN)-derived …

RhoGTPase regulators orchestrate distinct stages of synaptic development

S Martin-Vilchez, L Whitmore, H Asmussen, J Zareno… - PLoS …, 2017 - journals.plos.org
… cone development, axon guidance, and post-synaptic spine … in primary rat hippocampal
neurons cultured for either 1 or 2 … that unique combinations of Rho GTPase family members …

Spatiotemporal regulation of Rho GTPases in neuronal migration

Z Xu, Y Chen, Y Chen - Cells, 2019 - mdpi.com
… of projection neurons in the developing cortex. The role of … process, while a thin axon appears
in the opposite direction [52… cytoplasmic dilation in migrating hippocampal neurons [105]. …

Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons

R Pennucci, I Gucciardi, I de Curtis - PLoS One, 2019 - journals.plos.org
… in double knockout hippocampal cultures. We show that the Rac3 … developing hippocampal
neurons. Overexpression of either GTPase in WT neurons increases the density of dendritic

Rho GTPase-activating proteins: Regulators of Rho GTPase activity in neuronal development and CNS diseases

GH Huang, ZL Sun, HJ Li, DF Feng - Molecular and Cellular Neuroscience, 2017 - Elsevier
… During brain development, each neuron typically outgrowths several neurites, … axon and
spine development. We try to explore how these RhoGAPs regulate the specific Rho GTPases

Rho GTPases in the physiology and pathophysiology of peripheral sensory neurons

T Kalpachidou, L Spiecker, M Kress, S Quarta - Cells, 2019 - mdpi.com
developmentRho GTPases-associated signals regulate neuronal migration and
morphogenesis, including processes, such as axonal polarization, axon growth and guidance, …

Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons

D Vallejo, CB Lindsay… - Journal of …, 2021 - Wiley Online Library
… in the regulation of Cofilin through Rac1 and Cdc42 in hippocampal neurons, we employed
selective inhibitors for each small Rho GTPase that directly target the GEF-binding domain (…

[HTML][HTML] The role of Rac GTPase in dendritic spine morphogenesis and memory

JF Costa, M Dines, R Lamprecht - Frontiers in synaptic neuroscience, 2020 - frontiersin.org
… For example, the normal distribution of filamentous actin (higher level of filamentous actin
in spines compared to the adjacent dendritic area) in hippocampal neurons, was disrupted in …

Rac-maninoff and Rho-vel: The symphony of Rho-GTPase signaling at excitatory synapses

JG Duman, FA Blanco, CA Cronkite, Q Ru… - … GTPases, 2022 - Taylor & Francis
… flows from the axon of one neuron to the dendrite or cell … essential for dendritic growth arrest
in hippocampal neurons [… has different effects on the development of hippocampal circuits […