Control of dendritic spine morphological and functional plasticity by small GTPases
KM Woolfrey, DP Srivastava - Neural plasticity, 2016 - Wiley Online Library
… neuron’s axon is much thinner than the dendrite … in hippocampal neurons [65]. Interestingly,
the spatiotemporal dynamics of Ras activation was again different to that of the Rho GTPases…
the spatiotemporal dynamics of Ras activation was again different to that of the Rho GTPases…
Rab GTPase signaling in neurite outgrowth and axon specification
D Villarroel‐Campos, FC Bronfman… - …, 2016 - Wiley Online Library
… In cultured hippocampal neurons, for example, axon determination during neuronal
polarization is preceded by bulk cytoplasmic flow and polarized trans-Golgi network (TGN)-derived …
polarization is preceded by bulk cytoplasmic flow and polarized trans-Golgi network (TGN)-derived …
RhoGTPase regulators orchestrate distinct stages of synaptic development
S Martin-Vilchez, L Whitmore, H Asmussen, J Zareno… - PLoS …, 2017 - journals.plos.org
… cone development, axon guidance, and post-synaptic spine … in primary rat hippocampal
neurons cultured for either 1 or 2 … that unique combinations of Rho GTPase family members …
neurons cultured for either 1 or 2 … that unique combinations of Rho GTPase family members …
Spatiotemporal regulation of Rho GTPases in neuronal migration
Z Xu, Y Chen, Y Chen - Cells, 2019 - mdpi.com
… of projection neurons in the developing cortex. The role of … process, while a thin axon appears
in the opposite direction [52… cytoplasmic dilation in migrating hippocampal neurons [105]. …
in the opposite direction [52… cytoplasmic dilation in migrating hippocampal neurons [105]. …
Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons
R Pennucci, I Gucciardi, I de Curtis - PLoS One, 2019 - journals.plos.org
… in double knockout hippocampal cultures. We show that the Rac3 … developing hippocampal
neurons. Overexpression of either GTPase in WT neurons increases the density of dendritic …
neurons. Overexpression of either GTPase in WT neurons increases the density of dendritic …
Rho GTPase-activating proteins: Regulators of Rho GTPase activity in neuronal development and CNS diseases
GH Huang, ZL Sun, HJ Li, DF Feng - Molecular and Cellular Neuroscience, 2017 - Elsevier
… During brain development, each neuron typically outgrowths several neurites, … axon and
spine development. We try to explore how these RhoGAPs regulate the specific Rho GTPases …
spine development. We try to explore how these RhoGAPs regulate the specific Rho GTPases …
Rho GTPases in the physiology and pathophysiology of peripheral sensory neurons
… development … Rho GTPases-associated signals regulate neuronal migration and
morphogenesis, including processes, such as axonal polarization, axon growth and guidance, …
morphogenesis, including processes, such as axonal polarization, axon growth and guidance, …
Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons
D Vallejo, CB Lindsay… - Journal of …, 2021 - Wiley Online Library
… in the regulation of Cofilin through Rac1 and Cdc42 in hippocampal neurons, we employed
selective inhibitors for each small Rho GTPase that directly target the GEF-binding domain (…
selective inhibitors for each small Rho GTPase that directly target the GEF-binding domain (…
[HTML][HTML] The role of Rac GTPase in dendritic spine morphogenesis and memory
JF Costa, M Dines, R Lamprecht - Frontiers in synaptic neuroscience, 2020 - frontiersin.org
… For example, the normal distribution of filamentous actin (higher level of filamentous actin
in spines compared to the adjacent dendritic area) in hippocampal neurons, was disrupted in …
in spines compared to the adjacent dendritic area) in hippocampal neurons, was disrupted in …
Rac-maninoff and Rho-vel: The symphony of Rho-GTPase signaling at excitatory synapses
JG Duman, FA Blanco, CA Cronkite, Q Ru… - … GTPases, 2022 - Taylor & Francis
… flows from the axon of one neuron to the dendrite or cell … essential for dendritic growth arrest
in hippocampal neurons [… has different effects on the development of hippocampal circuits […
in hippocampal neurons [… has different effects on the development of hippocampal circuits […