… processes, such as inflammation and autoimmunity 4, 6. … role in neuroprotection and central
nervous system (CNS) … from postsynaptic neurons and target presynaptic CB1R to suppress …

… CB1 and CB2 cannabinoid receptors also act to regulate the … These signaling pathways are
directly related to the variety of … receptors are found mainly in the nociceptive neurons of the …

… In addition, cannabinoid receptor 2 (CB2) signaling suppresses the … in presynaptic nerve
cells in the central nervous system, … can be directly targeted to prevent or treat inflammatory and …

… several mechanisms that involve neuronal and immune cells. Here, we constructed … Treating
autoimmune disease in the CNS without causing general immune suppression is a major …

… via the cannabinoid receptor 1 (CB 1 ); cannabinoid receptor 2 (… different cannabinoids are
not directly associated with CB 1 /… neurons by anandamide from inflammatory damage via the …

… in neuronal and glial cell generation in the developing CNS [… employed an experimental
autoimmune encephalomyelitis (… This has to be achieved by either employing a direct strategy…

… The ability of the cannabinoid receptors to act through these … of neurons, inhibition of
neurotransmitter release, changes in … /anti-CD28 antibodies act directly on the T cell receptor …

… , can interact with cannabinoid receptors (CB1 and CB2) … cells and the destruction of the
neuron myelin sheath. CBD is used … In this study, the COR167 (CB2 agonist) effect was directly …

… was suppressing the production of the pro-inflammatory … roles of the classical cannabinoid
receptors CB1 and CB2 by use … the direct effects of CBD on IL-1β production by inflammatory …

… damages of experimental autoimmune encephalomyelitis (… immune cells mediated by
cannabinoid receptors, which encourage … by neurons was required for cannabinoid-mediated EAE …