… and metabolic risk factors for cognitive decline in AD were evaluated. … metabolism can be
disrupted in AD/aMCI patients, leading to neuronal damage in related brain regions, cognitive …

… are the main inhibitory neurons in the central nervous system (… neural circuitry and activity,
cognitive function-related neural … Dysfunctional GABA interneuron activity can disrupt the …

… pathology, and the starting point of the network disruption and cognitive impairment. …
neuronal circuits and brain networks. In both AD mice models and human preclinical AD data, …

… between the impaired connectivity and the cognitive decline is often … for the disruption of
neuronal circuits in AD, but we are still faced with the question of whether the circuit disruption is …

… activity lead to neuronal damage and dysfunction and, … a link between metabolic dysfunction
and cognitive decline. … The decrease in tight junction protein expression and the disturbed …

… degeneration have been shown to influence the cognitive decline in genetic- or diet-induced …
Cognitive function was impaired in rats of a high-energy diet and disruption of BBB integrity …

… Reduced glucose availability in neurons may disrupt … the ability of neurons to respond to the
high-energy demands associated … coupled to cognitive function, abnormal metabolism in the …

… disrupt metabolism and alter cognitive and affective behavior in adolescent rats. To test this
hypothesis, we followed the metabolic, … to the susceptibility of specific neural circuits in critical …

… , neural dynamics and their energetic sequelae are disrupted in neurological and psychiatric
disorders, with devastating consequences for cognitive … associated with cognitive decline in …

… stress, disruption of cell membranes, Ca 2+ dyshomeostasis, mitochondrial … neuron-specific
PGC-1α (nPGC-1α) after BCAS surgery showed an improvement in cognitive function …