… we studied age acceleration using three different … correlation with age of onset (r=−0.55,
p=0.0098, Supplementary Figure 3B). Age of onset was highly correlated with chronological age …

… a significant reverse correlation of DNAm age-acceleration with … of chronological age
across different tissues [10]. DNAm … Our findings strongly suggest that increased DNAm age-…

… a highly accurate molecular correlate of chronological age in … DNA methylation marks that
are strongly correlated (r ≥ 0.8 [… Each DNA methylation clock that is constructed is unique to its …

… distinct age-related methylation profiles [9–12]. While this global ‘epigenetic clock’ correlates
strongly with chronological age … of samples in different age classes was different, we ran a …

… between their DNA methylation level and chronological age during … The distinct roles
of the methylation status were … of aging-association analysis and combined PCA-correlation …

… Different tissues may have distinct DNA methylation profiles; … chronological age, and the
y-axis is the estimated DNAm age. … whose hypermethylation is strongly correlated with age [59,…

… , the high instability in detection and low correlation with age-… age (ie, DNA methylation age)
and chronological age, often symbolized as Δage (DNA methylation age – chronological age…

… of chronological age, the pace of biological age varies among individuals and may predict
distinct aspects of aging at different … 88 CpGs that correlated with the chronological age of 34 …

… not capture the unique aging changes in the brain. A notable … similar correlation between
predicted and chronological age … of DNA methylation change and higher order changes like …

… We hypothesized that methylation age would be accelerated, not just in high-grade … Distinct
DNA methylation changes highly correlated with chronological age in the human brain. Hum …