[HTML][HTML] Therapeutic implications of miRNAs for muscle-wasting conditions

L Yedigaryan, M Sampaolesi - Cells, 2021 - mdpi.com
… Myotonic dystrophy is characterized by progressive myotonia, muscle weakness, and
multiorgan involvement. There are two distinct types of myotonic dystrophy: myotonic dystrophy …

[HTML][HTML] MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sjögren's syndrome

JQ Chen, G Papp, S Póliska, K Szabó, T Tarr, BL Bálint… - PloS one, 2017 - journals.plos.org
diseases. The aim of our study was to examine the changes in miRNA expression profiles in
… of miR-150-5p, which is a novel and unique finding in pSS. Levels of several miRNAs over-…

[HTML][HTML] microRNA-mRNA profile of skeletal muscle differentiation and relevance to congenital myotonic dystrophy

SU Morton, CR Sefton, H Zhang, M Dai… - International Journal of …, 2021 - mdpi.com
… In this study, we analyze mRNA and miRNA expression data … , and unique miRNA expression
patterns were identified and … miRNAs as potential therapeutic targets in muscle disorders. …

[HTML][HTML] Muscle-specific microRNAs in skeletal muscle development

M Horak, J Novak, J Bienertova-Vasku - Developmental biology, 2016 - Elsevier
… skeletal muscle development and its functions may lead to numerous health conditions
Moreover, it has been observed that in some instances miRNA expression is controlled by …

[HTML][HTML] Circulating miRNAs are generic and versatile therapeutic monitoring biomarkers in muscular dystrophies

D Israeli, J Poupiot, F Amor, K Charton, W Lostal… - Scientific reports, 2016 - nature.com
… demonstrated distinct miRNA profiles in muscle biopsies of 10 primary muscular disorders. …
MiRNA expression was assessed in the Ga muscle of the KO-Sgca dystrophic mice, 3 months …

[HTML][HTML] Differential expression of microRNAs and other small RNAs in muscle tissue of patients with ALS and healthy age-matched controls

A Kovanda, L Leonardis, J Zidar, B Koritnik… - Scientific reports, 2018 - nature.com
… and various muscle disorders and indicate muscle tissue is … global miRNA expression is
lacking, and the expression of … muscles of ALS patients, and we were therefore in a unique

[HTML][HTML] Identification of circulating miRNAs differentially expressed in patients with Limb-girdle, Duchenne or facioscapulohumeral muscular dystrophies

JL García-Giménez, ER García-Trevijano… - … journal of rare diseases, 2022 - Springer
… and muscle biopsies to identify uniquemuscle diseases, some of them were found to be
expressed in a disease-specific manner. MyomiRs dysregulation was first observed in muscle

[PDF][PDF] Regulation of skeletal muscle by microRNAs

GP Diniz, DZ Wang - Compr. Physiol, 2016 - researchgate.net
… almost all samples, it was impossible to identify distinctive patterns of miRNA expression
associated with each type of primary muscle disorder. These findings may contribute to identify …

[HTML][HTML] MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours

AL Leichter, MJ Sullivan, MR Eccles, A Chatterjee - Molecular cancer, 2017 - Springer
… in miRNA expression profiles may heavily impact the development, differentiation, and
control of growth leading to diseases … Further, there were distinct mechanisms also identified; …

[HTML][HTML] miRNA profiling for early detection and treatment of duchenne muscular dystrophy

HC Hrach, M Mangone - International journal of molecular sciences, 2019 - mdpi.com
… genes are located in clusters, transcribed with unique promoters, or found in intronic regions
… of human neuromuscular diseases [6,7]. For example, changes in miRNA expression have …