[HTML][HTML] Therapeutic implications of miRNAs for muscle-wasting conditions
L Yedigaryan, M Sampaolesi - Cells, 2021 - mdpi.com
… Myotonic dystrophy is characterized by progressive myotonia, muscle weakness, and
multiorgan involvement. There are two distinct types of myotonic dystrophy: myotonic dystrophy …
multiorgan involvement. There are two distinct types of myotonic dystrophy: myotonic dystrophy …
[HTML][HTML] MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sjögren's syndrome
… diseases. The aim of our study was to examine the changes in miRNA expression profiles in
… of miR-150-5p, which is a novel and unique finding in pSS. Levels of several miRNAs over-…
… of miR-150-5p, which is a novel and unique finding in pSS. Levels of several miRNAs over-…
[HTML][HTML] microRNA-mRNA profile of skeletal muscle differentiation and relevance to congenital myotonic dystrophy
SU Morton, CR Sefton, H Zhang, M Dai… - International Journal of …, 2021 - mdpi.com
… In this study, we analyze mRNA and miRNA expression data … , and unique miRNA expression
patterns were identified and … miRNAs as potential therapeutic targets in muscle disorders. …
patterns were identified and … miRNAs as potential therapeutic targets in muscle disorders. …
[HTML][HTML] Muscle-specific microRNAs in skeletal muscle development
M Horak, J Novak, J Bienertova-Vasku - Developmental biology, 2016 - Elsevier
… skeletal muscle development and its functions may lead to numerous health conditions …
Moreover, it has been observed that in some instances miRNA expression is controlled by …
Moreover, it has been observed that in some instances miRNA expression is controlled by …
[HTML][HTML] Circulating miRNAs are generic and versatile therapeutic monitoring biomarkers in muscular dystrophies
D Israeli, J Poupiot, F Amor, K Charton, W Lostal… - Scientific reports, 2016 - nature.com
… demonstrated distinct miRNA profiles in muscle biopsies of 10 primary muscular disorders. …
MiRNA expression was assessed in the Ga muscle of the KO-Sgca dystrophic mice, 3 months …
MiRNA expression was assessed in the Ga muscle of the KO-Sgca dystrophic mice, 3 months …
[HTML][HTML] Differential expression of microRNAs and other small RNAs in muscle tissue of patients with ALS and healthy age-matched controls
A Kovanda, L Leonardis, J Zidar, B Koritnik… - Scientific reports, 2018 - nature.com
… and various muscle disorders and indicate muscle tissue is … global miRNA expression is
lacking, and the expression of … muscles of ALS patients, and we were therefore in a unique …
lacking, and the expression of … muscles of ALS patients, and we were therefore in a unique …
[HTML][HTML] Identification of circulating miRNAs differentially expressed in patients with Limb-girdle, Duchenne or facioscapulohumeral muscular dystrophies
JL García-Giménez, ER García-Trevijano… - … journal of rare diseases, 2022 - Springer
… and muscle biopsies to identify unique … muscle diseases, some of them were found to be
expressed in a disease-specific manner. MyomiRs dysregulation was first observed in muscle …
expressed in a disease-specific manner. MyomiRs dysregulation was first observed in muscle …
[PDF][PDF] Regulation of skeletal muscle by microRNAs
… almost all samples, it was impossible to identify distinctive patterns of miRNA expression
associated with each type of primary muscle disorder. These findings may contribute to identify …
associated with each type of primary muscle disorder. These findings may contribute to identify …
[HTML][HTML] MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours
… in miRNA expression profiles may heavily impact the development, differentiation, and
control of growth leading to diseases … Further, there were distinct mechanisms also identified; …
control of growth leading to diseases … Further, there were distinct mechanisms also identified; …
[HTML][HTML] miRNA profiling for early detection and treatment of duchenne muscular dystrophy
HC Hrach, M Mangone - International journal of molecular sciences, 2019 - mdpi.com
… genes are located in clusters, transcribed with unique promoters, or found in intronic regions
… of human neuromuscular diseases [6,7]. For example, changes in miRNA expression have …
… of human neuromuscular diseases [6,7]. For example, changes in miRNA expression have …