Extracellular matrix, integrins, and focal adhesion signaling in polycystic kidney disease

Y Zhang, G Reif, DP Wallace - Cellular signalling, 2020 - Elsevier
… The β 1 -integrin subunit is the most prevalent β-subunit in the kidney, and it combines
with several different α-integrin subunits. In normal fetal kidneys, α 2 - and α 3 - subunits are …

[HTML][HTML] Fetal reprogramming of nutrient surplus signaling, O-GlcNAcylation, and the evolution of CKD

M Packer - Journal of the American Society of Nephrology, 2023 - journals.lww.com
… SIRT1 defines its spatiotemporal distribution and functionality, … nondiabetic kidney disorders
(eg, polycystic kidney disease … α-actinin 4, and α-integrin, cytoskeletal proteins that maintain …

[HTML][HTML] Mesenchymal stem cells in fibrotic diseases—The two sides of the same coin

L Qin, N Liu, C Bao, D Yang, G Ma, W Yi… - Acta Pharmacologica …, 2023 - nature.com
… Type V and VI collagen have been reported to interact with α-Integrin receptors in cardiac
fibroblasts and promote the differentiation of myofibroblasts [48, 49]. Decreased secretion of …

Polymer hydrogels to guide organotypic and organoid cultures

V Magno, A Meinhardt, C Werner - Advanced Functional …, 2020 - Wiley Online Library
… The development of a mammalian embryo from the fetus to a … shown to be regulated by the
distribution of heparan- and … β1-integrin signaling involving various α-integrin subunits (α 5 , α …

[图书][B] Unravelling the Cell Adhesion Defect in Meckel-Gruber Syndrome

BRA Meadows - 2017 - search.proquest.com
… heritable human disease characterised by CNS malformations, cystic kidney, polydactyly, and
… Some integrins have tightly limited distribution and a restricted set of binding partners, and …

AP-1B facilitates endocytosis during cell migration

MJ Kell, SF Ang, L Pigati, A Halpern, H Fölsch - bioRxiv, 2019 - biorxiv.org
diseases such as metastatic cancer and polycystic kidney … Major sorting stations for the
polarized delivery of cargos to the … by recognition of a selected α integrin subunit to AP-2 through …

[图书][B] Identification of the Cell Receptors for Fibulin-4 and Latent Transforming Growth Factor-β Binding Protein-4, and their Functional Roles in Elastogenesis

H Hakami - 2020 - search.proquest.com
… The total protein sequence of each integrin varies between 750-1000 amino acid residues
but typically α integrin subunits are larger than β subunits296. All α subunits have four to five …

[HTML][HTML] Location, location, location: how vascular specialization influences hematopoietic fates during development

AM Heck, T Ishida, B Hadland - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
… erythrocytes necessary for oxygen delivery in the developing … also found that CD51, another
α integrin that can form a co-… Ezh2 in fetal liver ECs mediates fetal erythropoiesis through …

Basement Membranes Mediate Interactions Between Tissues

SG Payne - 2022 - search.proquest.com
… signaling through binding to signaling molecules, or insulation of signaling cues within an
encasement of BM, but BMs can also control signaling through degradation and breakdown. …

[PDF][PDF] TOWARDS DEFINING THE ENDOMEMBRANE COMPARTMENTS OPERATING IN CELLULAR EXIT OF CORONVIRUSES

M Enyioko - 2021 - bora.uib.no
… into its amino terminal S1 subunit and carboxyl terminal S2 subunit. S1 enables the virus to
… compartment during its delivery to the PM [71]. The Drosophila α-integrin again has been …