Are cytostatic drugs in surface waters a potential threat?

TIA Gouveia, IH Mota, AMT Silva, A Alves… - … The Total Environment, 2022 - Elsevier
… to cancer patients under chemotherapy. Their occurrence in … presence of cytostatic drugs in
Portuguese rivers. Furthermore… or wastewater treatment plants' discharge points. After being …

[HTML][HTML] New insights on cytostatic drug risk assessment in aquatic environments based on measured concentrations in surface waters

TIA Gouveia, A Alves, MSF Santos - Environment international, 2019 - Elsevier
… ; thus, these compounds are ultimately discharged into the environment. A total of 36 studies
Cytotoxic drugs and the aquatic environment: estimation of bleomycin in river and water …

Environmental risk assessment of widely used anticancer drugs (5-fluorouracil, cisplatin, etoposide, imatinib mesylate)

M Mišík, M Filipic, A Nersesyan, M Kundi, M Isidori… - Water research, 2019 - Elsevier
… other frequently used cytostatic drugs and combined effects … The present article focuses
mainly on environmental RAs on … inhibitors used for targeted chemotherapy. It was developed in …

A case study to identify priority cytostatic contaminants in hospital effluents

A Olalla, N Negreira, ML de Alda, D Barceló… - Chemosphere, 2018 - Elsevier
Drugs have been discharged into the environment without … Cytostatic drugs are used in
chemotherapy to treat … of their presence and concentration in river water given their direct effect …

Anticancer drugs in wastewater and natural environments: A review on their occurrence, environmental persistence, treatment, and ecological risks

A Castellano-Hinojosa, MJ Gallardo-Altamirano… - Journal of Hazardous …, 2023 - Elsevier
drugs used in chemotherapy and anticancer medication have … ), and rivers where the WWTP
discharges the treated water, is … anticancer drugs are designed to induce generic cytotoxicity

Local environmental risk assessment of anticancer drugs in a developing country

RF da Silva, L de Lima Moura, LO Gavião… - … and Ecological Risk …, 2020 - Taylor & Francis
… most sewage is still released into untreated receiving bodies. … to predict environmental
concentrations of cytostatic drugs … the rivers or sea. The evaluation of the 100 largest Brazilian …

[HTML][HTML] Anticancer drugs in the aquatic ecosystem: Environmental occurrence, ecotoxicological effect and risk assessment

D Li, H Chen, H Liu, D Schlenk, J Mu, S Lacorte… - Environment …, 2021 - Elsevier
… , into 2 main classes: cytotoxic agents and endocrine therapy … of the Jingmei River receiving
hospital discharge were up to … used in chemotherapy for cancer can be classified into four …

[HTML][HTML] Cytostatic pharmaceuticals as water contaminants

M Jureczko, J Kalka - European journal of pharmacology, 2020 - Elsevier
… , cytostatic drugs have become a great environmental threat. … are released into rivers and
lakes, so anticancer drugs can … caused by chemotherapy drugs. In a foetus, these mutations …

Source, Occurrence, and Risk Assessment of Antineoplastic Medicines in Aquatic Environments: A Comprehensive Review

A Yadav, ER Rene, M Sharma, V Kumar… - Current Pollution …, 2023 - Springer
drugs, also known as anti-cancerous agents, are cytostatic in … wastewater, and even in rivers
with a concentration range of … discharge of antineoplastic medication residues into aquatic …

Cytostatics in Dutch surface water: Use, presence and risks to the aquatic environment

C Moermond, B Venhuis, M van Elk, A Oostlander… - 2018 - rivm.openrepository.com
cytostatic residues end up in waste water that is treated in waste water treatment plants and
subsequently discharged into … in the majority of European rivers, concentrations of cytostatics …