Spacers versus nebulizers in treatment of acute asthma–a prospective randomized study in preschool children

N Mitselou, G Hedlin, CA Hederos - Journal of Asthma, 2016 - Taylor & Francis
… Our data suggests that the efficacy of inhaled beta 2 agonists administered using the spacer
device does not differ from that of the nebulizer. These findings are in agreement with those …

Currently available inhaled therapies in asthma and advances in drug delivery and devices

B Thomas, A Pugalenthi - Indian journal of pediatrics, 2022 - Springer
… (ICS), short-acting β 2 agonists (SABA), long-acting β 2 … In addition to improving drug delivery
to the airways, spacers … —jet nebulizers, ultrasonic nebulizers, mesh nebulizers, and smart …

Comparison of effectiveness of metered dose inhaler with spacer and jet nebulizer in children aged 5–14 years with acute exacerbation of asthma: A pilot randomized …

K Mittal, R Batra, A Khanna - Journal of Pediatric Critical Care, 2021 - journals.lww.com
… includes inhaled short-acting β2-agonists (SABA). The aim of … the device actuation and
inhalation due to lack of patient … the effectiveness of these two drug delivery systems in 100 …

Spacers versus Nebulizers in Treatment of Acute Asthma A Prospective Randomized Study in Preschool Children

MB Hamza, AI Harkan - The Egyptian Journal of Hospital Medicine, 2022 - journals.ekb.eg
… of children who use MDIs without devices, such as a spacers … some forgiveness in medication
delivery even when misused … The children were given either 4 ml of inhaled beta-2-agonist

[PDF][PDF] The use of metered-dose inhaler versus nebulization for the delivery of salbutamol in pediatric severe asthma exacerbations: A systematic review

KT Perez, BP MANDANAS-PAZ - … of the Philippine Children's Medical …, 2022 - pcmc.gov.ph
… of MDI with spacers versus nebulizers in drug delivery of … of salbutamol, a short-acting
beta-agonist (1). Recent randomized … nebulization and find the noise produced by the device as …

Metered‐dose inhalers vs nebulization for the delivery of albuterol in pediatric asthma exacerbations: A cost‐effectiveness analysis in a middle‐income country

CE Rodriguez‐Martinez… - Pediatric …, 2020 - Wiley Online Library
… (spacers) compared to nebulizers for the delivery of beta2-agonists for acute asthma 9 that
… costs of medications and delivery devices for each of the two modes of delivery of albuterol, …

Comparison of two inhalational techniques for bronchodilator administration in children and adolescents with acute asthma crisis: a meta-analysis

C Roncada, J Andrade, LC Bischoff… - Revista Paulista de …, 2018 - SciELO Brasil
… by nebulizer versus spacer device in children with acute asthma. J Pediatr. 1993;123:313-7. …
there are no differences in the administration of β-2 agonist via MDI-spacer or nebulizer. …

Assessing the viability of long-acting β2-agonists in paediatric asthma patients: a pharmacokinetic/pharmacodynamic perspective

MG Matera, B Rinaldi, L Calzetta… - Expert Opinion on Drug …, 2017 - Taylor & Francis
device used, a maximum of 10% of the inhaled dose of a β 2 -… Metered Dose Inhaler (pMDI),
the amount of drug delivered to … to a spacer (pMDI-spacer) with that of a nebulizer to deliver

10. PEDIATRIC USES OF NEBULIZERS

PW Barry - api.taylorfrancis.com
… other drug delivery devices are not tolerated by the patient or are … saturation following nebulized
beta-2-agonists has also been … to a spacer may markedly affect drug delivery to children. …

Aerosolized drug delivery in awake and anesthetized children to treat bronchospasm

N Anderson, S Clarke… - Pediatric …, 2022 - Wiley Online Library
… , a non-selective adrenergic agonist—to reduce … drug product (eg, nebulizers, spacers).
Clinicians have to keep in mind that device-only products are not required to conform with drug-…