… ERK1/2 is abundant in the adult brain, and its activation can play multiple roles in the activity…
ERK1/2 signaling pathway and a variety of neurological diseases, including stroke, neuro-…

… For quantification, we counted the number of live/dead cells within two sectors per well (at …
of 0.5 mg/kg of U0126 (Cell Signaling Technology) at the beginning of the reperfusion. Control …

… the intervention with CH-I and CBL, the expression of pMEK1/2 in both two groups was …
after stroke. Some evidence has shown that CIRI can activate the MAPK/ERK1/2 signal pathway, …

… used in the treatment of IS in China and have a wide range of therapeutic effects on IS by
regulating multiple targets and signaling pathways. The keywords “ischemia stroke, traditional …

… After reperfusion, the CBF of two groups almost returned to normal level. The volume of …
Besides, the role of the MAPK/ERK1/2 pathway in ischemic stroke is controversial. Because …

… 1/2 signaling pathway performs multiple regulatory functions … Thrombolytic therapy is the
most effective treatment for stroke … Akt, VEGF, and MAPK/ERK1/2 signaling pathways, mediates …

… AS and LC have both been used to treat stroke in traditional … 1/1000 dilution, #4870 Cell
Signaling), as internal controls for the … p38 MAPK plays a dual role in the regulation of cell death. …

… acute stages of ischemic stroke (Cheng et al. 2016). We observed that phosphorylated p38
may be upregulated after ischemic stroke and reversed after EA intervention, demonstrating …

… ) followed by Tukey’s multiple comparisons test was used for multiple comparisons. P < 0.05
… makes EA a promising therapeutic strategy for stroke. However, the role of ERK1/2/Nrf2 in …

… We examined two features of Cx43 function that may be potential targets for neuroprotection,
specifically, the potential protective benefits provided by GJ coupling and the detrimental …