Lanthanide complexes in molecular magnetic resonance imaging and theranostics

S Lacerda, É Tóth - ChemMedChem, 2017 - Wiley Online Library
Lanthanide chelates have attracted particular attention in the … as magnetic resonance imaging
(MRI) contrast agents and … linked to the structural and dynamic properties of the chelate;10 …

Molecular magnetic resonance imaging probes based on Ln3+ complexes

CS Bonnet, E Toth - Advances in Inorganic Chemistry, 2016 - Elsevier
… , most often based on lanthanide chelates, opened new possibilities to create MRI contrast.
… In the third part of the review, we show examples from the field of lanthanide-based bimodal …

Applications for transition-metal chemistry in contrast-enhanced magnetic resonance imaging

A Gupta, P Caravan, WS Price… - Inorganic …, 2020 - ACS Publications
Dynamic imaging of GBCA uptake and washout from … + chelates that have been evaluated
as MRI contrast agents … across the lanthanide series, metal deposition from lanthanide-based …

Rare-earth based materials: an effective toolbox for brain imaging, therapy, monitoring and neuromodulation

Z Wei, Y Liu, B Li, J Li, S Lu, X Xing, K Liu… - Light: Science & …, 2022 - nature.com
… Moreover, the emission spectrum of the lanthanide (Ln) based … with DOTA moieties to chelate
Gd 3+ ions for high contrast MRI (Fig… b QDs-sensitized RENPs for high-contrast of dynamic

Molecular magnetic resonance imaging with Gd (III)-based contrast agents: challenges and key advances

H Li, TJ Meade - Journal of the American Chemical Society, 2019 - ACS Publications
… a suitable ligand or chelate must bind the lanthanide to form a bio-… The dynamic range of
the agent is related to the dissociation … possess superior cell permeability and similar relaxivity …

Chemical insights into the issues of Gd retention in the brain and other tissues upon the administration of Gd‐containing MRI contrast agents

E Gianolio, ED Gregorio, S Aime - European Journal of …, 2019 - Wiley Online Library
… strongly with the chelating agent for Gd 3+ ions, owing to the … the content of both the
lanthanides upon increasing the sacrifice … on the study of the dynamic and structural properties of …

Highly brain-permeable apoferritin nanocage with high dysprosium loading capacity as a new T2 contrast agent for ultra-high field magnetic resonance imaging

HK Kim, AR Baek, G Choi, J Lee, J Yang, H Jung… - Biomaterials, 2020 - Elsevier
… for a highly brain-permeable MR CA with high sensitivity at UHF by loading dysprosium
chelates (DyL) in apoferritin cavities (Apo-DyL). We also design the chelate ligand structure to …

Rare earth coordination chemistry in action: Exploring the optical and magnetic properties of the lanthanides in bioscience while challenging current theories

D Parker - Handbook on the Physics and Chemistry of Rare …, 2016 - Elsevier
… as contrast agents for magnetic resonance imaging and … Second, a chelating ligand was
required that could be linked … just as we examine the magnetic susceptibility tensor and its …

Design and synthesis of luminescent lanthanide-based bimodal nanoprobes for dual magnetic resonance (MR) and optical imaging

W Mnasri, M Parvizian, S Ammar-Merah - Nanomaterials, 2021 - mdpi.com
… metal and lanthanide complexes, are suitable for positive contrast (MR images in which areas
… both luminescent and paramagnetic lanthanides are simultaneously chelated. The design …

Gadolinium (iii) based nanoparticles for T 1-weighted magnetic resonance imaging probes

CT Yang, P Padmanabhan, BZ Gulyás - RSC advances, 2016 - pubs.rsc.org
… available Gd(III) chelates contrast agents in patients with severe … The dynamic contrast
imaging on SCID mice bearing … with other lanthanides to integrate optical and MR contrast effect …