Functionalized lanthanide oxide nanoparticles for tumor targeting, medical imaging, and therapy

MY Ahmad, H Yue, T Tegafaw, S Liu, SL Ho, GH Lee… - Pharmaceutics, 2021 - mdpi.com
… excellent imaging contrast, especially when contrast agents … distinguished from normal
tissues in a rat brain as shown in … , the long-term toxicity of clinically used Gd 3+ -chelates was …

Gadolinium-based bimodal probes to enhance T1-Weighted magnetic resonance/optical imaging

CT Yang, A Hattiholi, ST Selvan, SX Yan, WW Fang… - Acta biomaterialia, 2020 - Elsevier
… or chelates for contrast enhancement in MRI, while they are used as optical imaging probes
in … Lanthanide-doped UCNPs are a novel type of imaging probes with promising applications …

Metal-based environment-sensitive MRI contrast agents

CS Bonnet, É Tóth - Current Opinion in Chemical Biology, 2021 - Elsevier
… use of small Gd 3+ chelates, which are nonspecific and reveal … Relaxivity depends on structural
and dynamic parameters of … by the toxicity concerns linked to this lanthanide ion. By now, …

Lanthanide complexes for drug delivery and therapeutics

G Bao - Journal of Luminescence, 2020 - Elsevier
… effect, and chelating ligands of lanthanide complexes and … , lanthanide complexes are potential
candidates as contrast … R 3 peptide with improved cell-permeability. All the Er–R n and Yb…

An Investigation of Antenna, Ligand Side-chain, and Metal Ion Effects on the Optical and MRI Properties of Bimodal Lanthanide (III) Complexes

M Poveda - 2020 - repository.usfca.edu
… that utilize a paramagnetic lanthanide ion chelated with a ligand … utilize contrast agents
especially for imaging the brain and … ICG permeability in conjunction with MR images could offer …

Employing paramagnetic shift for responsive MRI probes

AC Harnden, D Parker, NJ Rogers - Coordination Chemistry Reviews, 2019 - Elsevier
… shifts in lanthanide complexes. Due to the large anisotropy of the magnetic susceptibility, …
relaxivity Gd 3+ contrast agents because they are imaged directly, against zero background, …

Biomedical applications of lanthanide complexes

V Mutreja - Materials Today: Proceedings, 2022 - Elsevier
… applications The usage of lanthanides chelates as contrast agent employed in clinical
examination like clot formation, artery blockage, blood vessel rupture or nervous system function. …

[图书][B] MRI contrast agents: From molecules to particles

S Laurent, C Henoumont, D Stanicki, S Boutry, E Lipani… - 2017 - Springer
… with other lanthanides, allowing efficient transfer of the magnetic … accompanied by a low
thermodynamic stability. The main … a pH sensitive contrast agent with 30 Gd chelates and 114 …

Magnetic nanomaterials as contrast agents for MRI

S Caspani, R Magalhães, JP Araújo, CT Sousa - Materials, 2020 - mdpi.com
… There are several transition and lanthanide metals with … III) chelates are the most suitable
paramagnetic contrast agents, … , and they possess a small positive magnetic susceptibility [62]. …

Gd-and Eu-loaded iron oxide@ silica core–shell nanocomposites as trimodal contrast agents for magnetic resonance imaging and optical imaging

SLC Pinho, J Sereno, AJ Abrunhosa… - Inorganic …, 2019 - ACS Publications
… 1 and T 2 contrast capabilities of the lanthanide-bearing NPs, … their magnetic susceptibility,
which causes negative contrast … (36) Such effects have been reported in animal brain studies …