Design, Development and Applications of the Silica-Based Contrast Agents in Magnetic Resonance Imaging

MA Chowdhury - Current Nanomedicine (Formerly: Recent …, 2018 - ingentaconnect.com
… develop MRI contrast agents principally used lanthanide-based… The effect of T1 contrast
enhancement of the Gd-chelated … characterised by a weak magnetic susceptibility, where the sus…

Fluorinated MRI contrast agents and their versatile applications in the biomedical field

E Hequet, C Henoumont, RN Muller… - Future medicinal …, 2019 - Taylor & Francis
… of FLAMEs to enhance the permeability and retention (EPR) effect, … In 1 H MRI, paramagnetic
chelates tend to be more … -labelled lanthanide complexes as probes for 19 F MR imaging. …

A review of the current evidence on gadolinium deposition in the brain

R Pullicino, M Radon, S Biswas, M Bhojak… - Clinical Neuroradiology, 2018 - Springer
… , gadolinium-based contrast agents have been linked to MRI … the rate of dissociation of the
chelate, and therefore the rate … , namely that DN susceptibility is increased after administration …

… the MR Imaging Sensitivity of Upconversion Nanoparticles by an Internal and External Incorporation of the Gd3+ Strategy for in Vivo Tumor-Targeted Imaging

H Du, J Yu, D Guo, W Yang, J Wang, B Zhang - Langmuir, 2016 - ACS Publications
chelation. DTPA was covalently bound to the amine groups of BSA, and the Gd 3+ ions were
chelated … In this study, the strategy to enhance the MR imaging contrast of UCNPs benefits …

Contrast agents in cardiovascular magnetic resonance imaging

DJ Murphy, RY Kwong - Cardiovascular Magnetic Resonance Imaging, 2019 - Springer
… are ideal MRI contrast agents, with the lanthanide metal … ion, which is attached to a chelator
to reduce toxicity. There are … ), inflow phenomena, susceptibility, and the tissue relaxation time…

Advances in imaging brain metabolism

F Hyder, DL Rothman - Annual review of biomedical …, 2017 - annualreviews.org
… ) are reflected by magnetic susceptibility contrast induced by … cyclen derivatives containing
paramagnetic lanthanide (Ln 3+ … , higher k 1 in Equation 5), chelate structure, and/or choice of …

Divalent europium-based contrast agents for magnetic resonance imaging

AL Batchev, MM Rashid, MJ Allen - … on the Physics and Chemistry of Rare …, 2023 - Elsevier
… , Eu II is the most accessible divalent lanthanide with a half-filled … Understanding the
relationships among metal chelate … relaxivity through improving molecular dynamics for both Gd III …

Targeted PET/MRI imaging super probes: a critical review of opportunities and challenges

A Kastelik-Hryniewiecka, P Jewula… - International Journal …, 2022 - Taylor & Francis
lanthanide elements such as gadolinium (Gd 3+ ) or the transition metal manganese (Mn 2+
). Most paramagnetic contrast … with different chelators (DOTA or DFO) or optical imaging dye (…

MRI‐based Sensors for In Vivo Imaging of Metal Ions in Biology

H Allouche‐Arnon, ND Tirukoti… - Israel Journal of …, 2017 - Wiley Online Library
… (chelate, protein, etc.) for ion-specific recognition to (ii) a MR … ,23 paramagnetic lanthanide
complexes have shown the ability … and the image acquisition protocol, the obtained contrast is …

[HTML][HTML] Surface impact on nanoparticle-based magnetic resonance imaging contrast agents

W Zhang, L Liu, H Chen, K Hu, I Delahunty, S Gao… - Theranostics, 2018 - ncbi.nlm.nih.gov
… T 1 contrast agents are gadolinium (Gd) chelates, and the … agents are often composed of
transition or lanthanide metal … is the diffusion dynamics of water molecules in the magnetic field …