In vitro three-dimensional modeling for prostate cancer

E Dondossola, C Paindelli - Biomaterials for 3D Tumor Modeling, 2020 - Elsevier
… stem cell (PSC) biology using patient-derived human prostatic tissues and … for culture in
CSC medium. The percentage of CSCs enriched in the resultant spheroids is very much dynamic

Three-dimensional cell cultures as an in vitro tool for prostate cancer modeling and drug discovery

F Fontana, M Raimondi, M Marzagalli… - International journal of …, 2020 - mdpi.com
spheroids involves their self-assemblance in non-adherent … the self-adhesion dynamics and
predict the aggregation kinetics of … Human prostate releases large amounts of nerve growth …

Sialylation of cell surface glycoproteins facilitates formation of 3D multicellular prostate cancer spheroids

S Haq - 2017 - search.proquest.com
Prostate cancer spheroid based three-dimensional culture models (referred to as
prostaspheres) have provided insight into prostate cancer biology by highlighting the importance …

Human organ‐specific 3D cancer models produced by the stromal selfassembly method of tissue engineering for the study of solid tumors

V Roy, B Magne, M Vaillancourt-Audet… - BioMed Research …, 2020 - Wiley Online Library
… In healthy tissues, ECM is a dynamic microenvironment … spheroids with a hypoxic core
embedded in self-assembled … , especially in breast, lung, prostate, and colorectal cancer studies […

In-air production of 3D co-culture tumor spheroid hydrogels for expedited drug screening

J Antunes, VM Gaspar, L Ferreira, M Monteiro… - Acta biomaterialia, 2019 - Elsevier
… 3D spheroid microgels for prostate cancer cells and human … The human prostate cancer
cell line (PC-3) was maintained … disease progression in a highly dynamic process. Moreover, …

Bioinstructive microparticles for self-assembly of mesenchymal stem Cell-3D tumor spheroids

LP Ferreira, VM Gaspar, JF Mano - Biomaterials, 2018 - Elsevier
… and sphere-like morphology was reproducible and tri-culture … 1), by using the liquid-overlay
technique, also known as … formed tumor spheroids present dynamic migration patterns and …

[HTML][HTML] IC50: an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation

Y Xu, G Pachnikova, H Wang, Y Wu… - Bosnian Journal of …, 2022 - ncbi.nlm.nih.gov
spheroids formation in the spheroids microplates was based on the cell clusters within a
shorter period, dynamic … 2D and 3D cultures of fast proliferating cells mostly overlap. However, …

Let's Go 3D! New Generation of Models for Evaluating Drug Response and Resistance in Prostate Cancer

T Petrić, M Sabol - International Journal of Molecular Sciences, 2023 - mdpi.com
Spheroid and organoid cultures are 3D cultures composed of multiple cells with distinct and
overlapping … due to the signals from dynamic cellular interactions between neighboring cells …

Natural and synthetic biomaterials for engineering multicellular tumor spheroids

A Kamatar, G Gunay, H Acar - Polymers, 2020 - mdpi.com
… techniques include culture via liquid overlay, hanging drop, … Dynamic reciprocity describes
the continuous, bidirectional … the proliferative activity of prostate cancer metastasis to bone […

Tissue-engineered human 3D model of bladder cancer for invasion study and drug discovery

CR Goulet, G Bernard, S Chabaud, A Couture… - Biomaterials, 2017 - Elsevier
… Indeed, conventional 2D culture systems cannot replicate the complexity, diversity and dynamic
nature … Moreover, compared to 2D monolayer culture, the 3D spheroid culture enhanced …