Oncogene-induced regulation of microRNA expression: Implications for cancer initiation, progression and therapy

AR Paliouras, T Monteverde, M Garofalo - Cancer Letters, 2018 - Elsevier
… levels are lower in tumours [16]. This was further elucidated … of MYC family transcription
factors and miRNAs has expanded … NF-κB is a transcription factor with a multitude of roles in …

Interplay among SNAIL transcription factor, microRNAs, long non-coding RNAs, and circular RNAs in the regulation of tumor growth and metastasis

K Skrzypek, M Majka - Cancers, 2020 - mdpi.com
… 2 (FGF2), epidermal growth factor (EGF), Harvey rat sarcoma … Some miRNAs can behave
as oncogenes favoring … activates the transcription of miR-21 to produce exosomes abundant in …

[HTML][HTML] The interaction between ETS transcription factor family members and microRNAs: a novel approach to cancer therapy

L Du, Y Liu, C Li, J Deng, Y Sang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
MiRNAs can target the 3’UTR of ETS factors and inhibit the … the parental gene and increases
parental gene expression. … suppressors, but some oncogenic miRNAs are also upregulated …

Exploring mechanisms of microRNA downregulation in cancer

M Williams, YY Cheng, C Blenkiron, G Reid - Microrna, 2017 - ingentaconnect.com
… some miRNAs are broadly repressed by transcription factors such … with oncogenic functions
have been identified, but miRNAsEGF decreases the abundance of microRNAs that restrain

[HTML][HTML] MicroRNAs involved in the EGFR pathway in glioblastoma

B Xu, J Mei, W Ji, Z Huo, Z Bian, J Jiao, X Li… - Biomedicine & …, 2021 - Elsevier
miRNAs may function as tumor suppressors or oncogenes [3]. … the expression of the epidermal
growth factor receptor (EGFR… C-myc, the common downstream transcription factor of TGF/β…

microRNAs with AAGUGC seed motif constitute an integral part of an oncogenic signaling network

Y Zhou, O Frings, RM Branca, J Boekel, C Le Sage… - Oncogene, 2017 - nature.com
… their impact on response to epidermal growth factor (EGFR)-… even if oncomotif-miRNAs target
E2F transcription factors, the net … EGF decreases the abundance of microRNAs that restrain

MicroRNA miR-191 targets the zinc finger transcription factor Egr-1 and suppresses intimal thickening after carotid injury

Y Li, LS McRobb, LM Khachigian - International Journal of Cardiology, 2016 - Elsevier
… group was reduced by approximately 50% compared with the precursor mimic miRNA
negative … This is the first report of the use of a miRNA to inhibit Egr-1 in the context of intimal …

Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer

HT Wu, HT Zhong, GW Li, JX Shen, QQ Ye… - Journal of translational …, 2020 - Springer
… -β, β-catenin, miRNA and other factors. Here, we summarize … antibody against human
epidermal growth factor receptor 2 (… be inhibited by nuclear enriched abundant transcript 1 …

[HTML][HTML] Inside the stemness engine: Mechanistic links between deregulated transcription factors and stemness in cancer

EH Ervin, R French, CH Chang, S Pauklin - Seminars in cancer biology, 2022 - Elsevier
transcription factors and stemness in cancer. In particular, we describe the role of master
transcription factors (… and RUNX), signalling-regulated transcription factors (SMAD, β-catenin, …

Regulatory mechanism of MicroRNA expression in cancer

Z Ali Syeda, SSS Langden, C Munkhzul, M Lee… - International journal of …, 2020 - mdpi.com
… Dysfunction of miRNAs disturbs expression of oncogenic or tumor-… methylation of miRNA
genomic loci and the transcription factor-… Epidermal growth factor receptor (EGFR) signaling is …