Thymic function failure is associated with human immunodeficiency virus disease progression

S Ferrando-Martinez… - … Infectious Diseases, 2017 - academic.oup.com
First, we analyzed all the patients (aged 1–75 years), to include different stages of thymic
In this work we present the largest collection of thymic function data in HIV-infected patients …

Recent thymus emigrant CD4+ T cells predict HIV disease progression in patients with perinatally acquired HIV

R Zakhour, DQ Tran, G Degaffe, CS Bell… - … Infectious Diseases, 2016 - academic.oup.com
… course with respect to HIV disease for perinatally HIV-infected patients. To this purpose, we
… respect to HIV disease at baseline (point of enrollment and collection of first blood sample). …

Influence of maternal HIV infection on fetal thymus size

CL Gasthaus, R Schmitz, K Hammer… - Journal of Perinatal …, 2019 - degruyter.com
… The sonographic presentation of the fetal thymus was first … may affect the development
of the fetal thymus gland and in … be found in older children of HIV-infected mothers [2]. The …

[PDF][PDF] Eosinophil-Associated Changes in Neonatal Thymic T Regulatory Cell Populations in HIV-Infected Pregnancies

EI Obeagu, GU Obeagu - Elite Journal of Health Science, 2024 - researchgate.net
thymic Tregs in the context of HIV-infected pregnancies adds a novel dimension to our
understanding of the immune landscape during early development.… in infants born to HIV-infected

[HTML][HTML] Immune development in HIV-exposed uninfected children born to HIV-infected women

M Miyamoto, AFTB Gouvêa, E Ono… - Revista do Instituto de …, 2017 - SciELO Brasil
… We have also evaluated thymic function by quantifying T-cell … development of the immune
system over the first year of life. … development with consequences such as impairment in the …

Immune activation is associated with decreased thymic function in asymptomatic, untreated HIV-infected individuals

T Manjati, H Ipp, B Nkambule - Southern African journal of HIV …, 2016 - journals.co.za
… few studies that have linked immune activation to thymic dysfunction in HIV-infected people.…
Early thymic dysfunction in children is also related to rapid progression to acquired immune …

[HTML][HTML] Thymic function as a predictor of immune recovery in chronically HIV-infected patients initiating antiretroviral therapy

R Rb-Silva, C Nobrega, C Azevedo, E Athayde… - Frontiers in …, 2019 - frontiersin.org
… adults and children infected by HIV present thymic alterations … been associated with disease
progression and poorer prognosis … immune recoveries that diverge soon after ART initiation. …

[HTML][HTML] Thymic output and CD4 T-cell reconstitution in HIV-infected children on early and interrupted antiretroviral treatment: evidence from the children with HIV early …

J Lewis, H Payne, AS Walker, K Otwombe… - Frontiers in …, 2017 - frontiersin.org
disease progression and increased mortality compared to … that early identification and treatment
of HIV-infected infants is … albeit below levels in uninfected children. Once stabilized, CD4 …

[HTML][HTML] Accelerated aging in perinatally HIV-infected children: clinical manifestations and pathogenetic mechanisms

E Chiappini, M Bianconi, A Dalzini, MR Petrara… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
… in neurological impairment between children and adults may … after neuronal development
has ended, while in children the … be the much higher thymic output of T-cells in children than in …

[HTML][HTML] Impact of early versus late antiretroviral treatment initiation on naive T lymphocytes in HIV-1-Infected children and adolescents–the-ANRS-EP59-CLEAC study

P Frange, T Montange, J Le Chenadec… - Frontiers in …, 2021 - frontiersin.org
… data were therefore collected for HIV-infected children via the … N and virological history in
either children or adolescents. … Our observations are consistent with lower de novo thymic T …