Edoxaban and the issue of drug-drug interactions: from pharmacology to clinical practice

A Corsini, N Ferri, M Proietti, G Boriani - Drugs, 2020 - Springer
… may represent a significant clinical advantage. Among NOACs, edoxaban is the last to reach
… agents, we will focus this review on drug interactions, considering edoxaban, a NOAC with …

Edoxaban: a comprehensive review of the pharmacology and clinical data for the management of atrial fibrillation and venous thromboembolism

ZA Stacy, WB Call, AP Hartmann, GL Peters… - Cardiology and …, 2016 - Springer
Edoxaban, an oral direct Xa inhibitor, may provide clinicians with an additional option in
patients … This review examines the pharmacology and clinical data of edoxaban as a therapeutic …

Clinical relevance of pharmacokinetic and pharmacodynamic properties of edoxaban when treating patients with atrial fibrillation and heart failure

N Aspromonte, F Colivicchi - Expert Opinion on Drug Metabolism & …, 2017 - Taylor & Francis
… Areas covered: This article reviews the key published studies on the pharmacology, clinical
efficacy and safety of edoxaban, the latest NOAC to receive approval for the AF indication. …

Edoxaban: A direct oral anticoagulant

M Poulakos, JN Walker, U Baig… - … Health-System Pharmacy, 2017 - academic.oup.com
… , the value of edoxaban needs to be assessed. The purpose of this review is to compare
published data on the efficacy and safety of edoxaban versus warfarin for management of …

Factors related to inappropriate edoxaban use

BM Jang, OS Lee, EJ Shin, EJ Cho… - … of clinical pharmacy …, 2019 - Wiley Online Library
… was to evaluate the appropriateness and clinical outcomes of edoxaban use, and to
determine the role of clinical pharmacists in improving the efficacy and safety of edoxaban use. …

Pharmacokinetics and pharmacodynamics of edoxaban, a non-vitamin K antagonist oral anticoagulant that inhibits clotting factor Xa

DA Parasrampuria, KE Truitt - Clinical pharmacokinetics, 2016 - Springer
… manuscript reviews the pharmacokinetic and pharmacodynamic properties of edoxaban. …
to contribute significantly to the overall pharmacological activity of edoxaban in subjects with at …

Factors associated with edoxaban concentration among patients with atrial fibrillation

SY Lin, CH Kuo, LT Ho, YB Liu, CF Huang… - … in Pharmacology, 2021 - frontiersin.org
… Asian population were thinner than the Western populations in general, whether the
impact of BMI on edoxaban exposure is clinically significant remained unclear from our data. …

Pharmacology and clinical development of factor XI inhibitors

A Greco, C Laudani, M Spagnolo, F Agnello, DC Faro… - Circulation, 2023 - Am Heart Assoc
… practice and to clarify which FXI inhibitor may be most suited for each clinical indication.
This article reviews the rationale, pharmacology, results of medium or small phase 2 studies, …

Pharmacological Review of Anticoagulants

HON Tsai - Anticoagulation Drugs-the Current State of the Art, 2020 - books.google.com
review the basic physiology of hemostasis, pharmacology of … medications are used in the
clinical setting. The mechanism of … edoxaban remains to be the most sensitive test for edoxaban

The factor xa inhibitor edoxaban for the prevention of stroke and systemic embolism in patients with atrial fibrillation

J Minguet, HM Sims, KH Smith… - … of Clinical Pharmacology, 2017 - Taylor & Francis
… mg edoxabanedoxaban (rather than switching from warfarin at a later date) may be more
beneficial. In the subset of patients who had their edoxaban dosage halved owing to clinical