Conclusion In hospitalized patients with acute pulmonary embolism use of a retrievable
inferior vena cava filter plus anticoagulation compared with anticoagulation alone does not
reduce the risk of symptomatic recurrent pulmonary embolism (PE) at 3 months. Summary
There has been a sharp increase in inferior vena cava (IVC) filter placement in recent years.
This included a use of IVC filters as add-on therapy to anticoagulation in unselected patients
presenting with acute venous thromboembolism (VTE). However, there is a paucity of data …

Importance Although retrievable inferior vena cava filters are frequently used in addition to
anticoagulation in patients with acute venous thromboembolism, their benefit− risk ratio is
unclear. Objective To evaluate the efficacy and safety of retrievable vena cava filters plus
anticoagulation versus anticoagulation alone for preventing pulmonary embolism
recurrence in patients presenting with acute pulmonary embolism and a high risk of
recurrence. Design, Setting, and Participants Randomized, open-label, blinded endpoint …