… Effects of grapefruit juice on pharmacokinetics and … of grapefruit juice with a lower dose
(150 mg/kg) of artemether achieved … , which suggests that site of induction is hepatic [92]. This …

… the antiplasmodial effect of XA on P. falciparum, and its effect on rat liver CYP enzymes in …
2000 and 2004: the effect of combination of control methods. Malaria journal, 5(1), 33. …

… in vivo by both artemether and artemisinin was suggested to be … In-vivo effects of the anesthetic,
benzocaine, on liver … human drug metabolising cytochrome P450 enzymes using liquid …

… back that causes liver injury. The present study aims to evaluate the effects of artemisinin in
… Thus, the objective of this project is to study the effect of artemisinin on LCA-induced liver …

… Artemether were administered in combination with … interfered with the hepatic disease,
reducing hepatic injury and fibrosis. … effect on reduction of worm burden, the use of combined drug …

… -based combination therapies (ACT) including artemether … action does have a detoxification
effect; however, several active metabolites that are simultaneously produced can cause liver …

… -schistosomal effect of artemether, while artesunate, arteether, or … grapefruit juice influences
the enzymatic activity of cytochrome P450 monooxigenases and cytochrome b5 in the liver […

… rate constant (kdeg) of drug metabolising enzymes (DMEs) is a … achieved in the gut and
liver, which ultimately affect the … combining its highly inducible potential, significant impact of …

… Abnormal results of liver enzyme are common in patients consuming amiodarone. … grapefruit
juice has a protective effect against amiodarone-induced nephrotoxicity in rats. This effect …

… the liver. This mechanism explains for the increase in the plasma concentration of certain
orally taken drugs under the impact of … to increase the oral bioavailability of artemether [17]. Gr …