Influence of Fractional Inspired Oxygen Tension on Lung Perfusion Distribution, Regional Ventilation, and Lung Volume during Mechanical Ventilation of Supine …

BM Ribeiro, MR Tucci, MH Victor Júnior, JR Melo… - …, 2024 - pubs.asahq.org
… by lung densities) was markedly lower at high Fio 2 and low … by hypoxic pulmonary
vasoconstriction in animal models has … decrease in some studies 13,41,42 and no additional …

Tomographic in vivo microscopy for the study of lung physiology at the alveolar level

G Lovric, R Mokso, F Arcadu, I Vogiatzis Oikonomidis… - Scientific reports, 2017 - nature.com
… for multiple scans of the same animal roughly added up to 90 Gy… probability density (PDF)
plot, a significant decrease in lung … of selected lung regions under quasi-static inflation with the …

Modeling the influence of gravity and the mechanical properties of elastin and collagen fibers on alveolar and lung pressure–volume curves

L Shi, J Herrmann, S Bou Jawde, JHT Bates, HT Nia… - Scientific reports, 2022 - nature.com
… due to a change in local transpulmonary pressure 2 . Alveolar compliance itself … change
in transpulmonary pressure that every alveolus in each region experiences during lung inflation

Radiologic evaluation of compensatory lung growth using computed tomography by comparison with histological data from a large animal model

K Ohata, TF Chen-Yoshikawa, M Hamaji, T Kubo… - Scientific Reports, 2022 - nature.com
… (d,e) The value changes of the average lung density (d) and … No apparent alveolar
hyperinflation was observed in the … regional lung expansion. CT data cover the entire area of the …

[HTML][HTML] Quantitative dual-energy computed tomography predicts regional perfusion heterogeneity in a model of acute lung injury

FU Kay, MA Beraldo, MAM Nakamura… - Journal of computer …, 2018 - journals.lww.com
blood volume and PBF values were normalized by lung … per-animal Pearson r coefficient for
all segmented zones: 3 zones per … and different degrees of lung inflation. The authors found …

Pulmonary CT and MRI phenotypes that help explain chronic pulmonary obstruction disease pathophysiology and outcomes

EA Hoffman, DA Lynch, RG Barr… - Journal of Magnetic …, 2016 - Wiley Online Library
regional assessment of perfused blood volume, when blood … at various static inflation
pressures which effectively reduces … were also shown in animal studies124. FDMRI exploits free-…

Pulmonary vascular effects of pulsed inhaled nitric oxide in COPD patients with pulmonary hypertension

B Hajian, J De Backer, W Vos… - … obstructive pulmonary …, 2016 - Taylor & Francis
… Based on this, we can describe regional flow distribution. The … In an animal model of persistent
PH of the newborn, … In our patients, there was an average increase of blood volume of 7.06…

Combined assessment of pulmonary ventilation and perfusion with single-energy computed tomography and image processing

Y Fujita, M Kent, E Wisner, L Johnson, J Stern, L Qi… - Academic radiology, 2021 - Elsevier
… provide spatial information about regional lung dysfunction (1)… has also been demonstrated
through animal studies (13, 14). … values of the lung tissues varied with the lung inflation level, …

Influence of inspiratory/expiratory CT registration on quantitative air trapping

O Weinheimer, BA Hoff, AB Fortuna… - Academic radiology, 2019 - Elsevier
… simulates the effect of variable regions of lung deformation … in an animal model that increased
lung pressure (ie inflation) … a higher overall CT lung density is achieved on expiration. For …

Role of positive end-expiratory pressure and regional transpulmonary pressure in asymmetrical lung injury

L Bastia, D Engelberts, K Osada, BH Katira… - American journal of …, 2021 - atsjournals.org
… CT scan slices in one animal with right lung injury and one … Lung density (Table E1) was
increased in the injured lung … the best compromise between collapse and hyperinflation. …