Regional ventilation is the main determinant of alveolar deposition of coarse particles in the supine healthy human lung during tidal breathing

RC Sá, KL Zeman, WD Bennett, GK Prisk… - … and Pulmonary Drug …, 2017 - liebertpub.com
… For the estimation of lung density, acquisition followed the work … of the local O 2 concentration
in lung tissue, and thus signal … Moreover, that PET-CT study provided much broader lung

Diffusion lung imaging with hyperpolarized gas MRI

DA Yablonskiy, AL Sukstanskii, JD Quirk - NMR in Biomedicine, 2017 - Wiley Online Library
… ’ regions of lung parenchyma 1. However, the clinical and … In small animal lungs, the
diffusion time Δ should be an order … of inflation. The results indicated that, during a 143 ± 18% …

What causes uneven aerosol deposition in the bronchoconstricted lung? A quantitative imaging study

EE Greenblatt, T Winkler, RS Harris… - … and pulmonary drug …, 2016 - liebertpub.com
lungs and regional deposition likely influences therapeutic effectiveness. (1,2) We previously
reported PET-… images, and that changes in blood volume can be estimated from the entire …

Imaging the injured lung: mechanisms of action and clinical use

M Cereda, Y Xin, A Goffi, J Herrmann, DW Kaczka… - …, 2019 - pubs.asahq.org
region of lung (more air, less tissue) would have a density of far … Within the normal inflation
range (–500 to –900 Hounsfield … in the right lung, and arterial hemoglobin O 2 saturation was …

Spatial heterogeneity of lung strain and aeration and regional inflammation during early lung injury assessed with PET/CT

G Motta-Ribeiro, T Winkler, S Hashimoto, MFV Melo - Academic radiology, 2019 - Elsevier
lung areas of hyperinflation (2) but also at the microscopic level. Experiments utilizing total
lung capacity maneuvers in excised dog … in regional lung density, clinically used for diagnosis, …

Close down the lungs and keep them resting to minimize ventilator-induced lung injury

P Pelosi, PRM Rocco, M Gama de Abreu - Critical Care, 2018 - Springer
… reduced pulmonary blood volume, and not by an action of PEEP per se [19, 20]. … regional
pulmonary inflammation [29]. In anesthetized sheep receiving intravenous endotoxin, FDG-PET

[HTML][HTML] Tidal changes in PaO2 and their relationship to cyclical lung recruitment/derecruitment in a porcine lung injury model

DC Crockett, JN Cronin, N Bommakanti, R Chen… - British Journal of …, 2019 - Elsevier
… used to examine the effects of individual animal and type of … redistribution of pulmonary
blood flow to regions with different … , CT-measured voxel density used as a surrogate marker of …

Noninvasive imaging methods for quantification of pulmonary edema and congestion: a systematic review

T Lindow, S Quadrelli, M Ugander - Cardiovascular Imaging, 2023 - jacc.org
regions away from which blood volume was redistributed. Naum et al 90 performed PET (H
2 … in anesthetized dogs was studied by inducing pulmonary edema through the inflation of a …

Cardiopulmonary resuscitation–associated lung edema (CRALE). A translational study

A Magliocca, E Rezoagli, D Zani… - American Journal of …, 2021 - atsjournals.org
… in each of the six lung lobes of each animal. To adjust the model for the within-… of lung
density from the ventral to the dorsal regions among groups. P value of the treatment effect by a 2-…

[HTML][HTML] Lung circulation

K Suresh, LA Shimoda - Comprehensive Physiology, 2016 - ncbi.nlm.nih.gov
… Factors controlling pulmonary blood flow include vascular structure, gravity, mechanical
effects of breathing, and the influence of neural and humoral factors. Pulmonary vascular tone is …