Antithrombotic drugs—pharmacology and perspectives

T Li, D Yuan, J Yuan - Coronary artery disease: Therapeutics and drug …, 2020 - Springer
… this process is called fibrinolysis. Normally, hemostasis and fibrinolysis are finely regulated
… poor metabolism of clopidogrel, resulting in inadequate drug effect and ultimately leading to …

[HTML][HTML] Platelet aggregometry testing: molecular mechanisms, techniques and clinical implications

K Koltai, G Kesmarky, G Feher, A Tibold… - … journal of molecular …, 2017 - mdpi.com
… Junctional adhesion molecule A (JAM-A) is rapidly phosphorilated during platelet activation
by … in hemostasis: thrombin generation, clotting, clot retraction and fibrinolytic activation [81]. …

[PDF][PDF] Aspirin plus clopidogrel for angina pectoris in coronary heart disease patients

X Zhang, J Chen, M Ding, N Zhang - Int J Clin Exp Med, 2018 - e-century.us
Effect of clopidogrel on adhesion molecules, hemostasis, and fibrinolysis in coronary
heart disease. J Cardiovasc Pharmacol 2008; 51: 616-620. [12] Valgimigli M and Biscaglia S. …

[HTML][HTML] Platelets are at the nexus of vascular diseases

H Lebas, K Yahiaoui, R Martos… - Frontiers in cardiovascular …, 2019 - frontiersin.org
… that platelets are crucial for human hemostasis, is based on … to recruit leukocytes, upregulate
adhesion molecules by EC and … percutaneous coronary intervention and/or fibrinolysis

[HTML][HTML] Factors affecting the formation and treatment of thrombosis by natural and synthetic compounds

A Lichota, EM Szewczyk, K Gwozdzinski - … journal of molecular sciences, 2020 - mdpi.com
adhesion molecule (ICAM-1) and vascular cell adhesion … ROS affecting the processes of
coagulation, fibrinolysis, … and clopidogrel alone in patients with a previous ischemic stroke and …

Fibrinogen and fibrin in hemostasis and thrombosis

S Kattula, JR Byrnes, AS Wolberg - … , thrombosis, and vascular …, 2017 - Am Heart Assoc
… may have profound effects on fibrin formation and mechanical and fibrinolytic stability. …
increased incidence of coronary artery disease, 81 myocardial infarction, 82 and ischemic stroke, …

[HTML][HTML] The role of genetic polymorphism and other factors on clopidogrel resistance (CR) in an Asian population with coronary heart disease (CHD)

MA Akkaif, NAA Daud, A Sha'aban, ML Ng… - Molecules, 2021 - mdpi.com
Clopidogrel is a widely-used antiplatelet drug. It is important for the treatment and prevention
of coronary heart disease. Clopidogrel can effectively reduce platelet activity and therefore …

[HTML][HTML] Current and novel antiplatelet therapies for the treatment of cardiovascular diseases

G Jourdi, M Lordkipanidze, A Philippe… - … journal of molecular …, 2021 - mdpi.com
… antiplatelet effect than clopidogrel [… fibrinolytic agent urokinase [165]. All these compounds
have displayed potent antithrombotic effects in preclinical models without affecting hemostasis

The effects of ginsenosides on platelet aggregation and vascular intima in the treatment of cardiovascular diseases: from molecular mechanisms to clinical …

BY Luo, JL Jiang, YF Fang, F Yang, MD Yin… - Pharmacological …, 2020 - Elsevier
… , fibrinolytic drugs, and even surgery in critical situations [4]. Among them, antiplatelet agents,
such as aspirin (ASP), clopidogrel, … via activating a series of coagulation cascades. It was …

… decrease platelet aggregation but have no effect on thrombin generation, fibrin clot structure, and fibrinolysis in pulmonary arterial hypertension: PAPAYA coagulation

A Siniarski, A Gąsecka, M Starczyński… - Platelets, 2022 - Taylor & Francis
… shown in many cardiovascular diseases, such as coronary artery disease, heart failure, or
… did not show any effect of PGI 2 analogues on coagulation and fibrinolysis parameters. The …