Overview of biological effects of melatonin on testis: A review

S Heidarizadi, Z Rashidi, C Jalili, M Gholami - Andrologia, 2022 - Wiley Online Library
… toxicity, improve sperm quality and it affects the testosterone … effects of melatonin as a natural
antioxidant on testicles and … mice that were treated with melatonin had a testicular tissue …

Evaluation of the protective effects of amifostine and melatonin against cisplatin induced testis injury via oxidative stress and apoptosis in rats

H Eren, T Mercantepe, L Tumkaya… - Experimental and …, 2020 - Elsevier
… cisplatin was used to induce testis tissue damage, and amifostine and melatonin were used
as … We observed that treatment with amifostine, melatonin and amifostine plus melatonin

Role of melatonin in mitigating chemotherapy-induced testicular dysfunction in Wistar rats

P Madhu, KP Reddy, PS Reddy - Drug and chemical toxicology, 2016 - Taylor & Francis
melatonin ameliorated the PVB-induced testicular toxicity. Co-administration of melatonin and
PVB restored the activities of testicular … These data indicate that melatonin pre-treatment is …

The role of melatonin on chemotherapy-induced reproductive toxicity

H Haghi-Aminjan, MH Asghari… - Journal of Pharmacy …, 2018 - academic.oup.com
… of melatonin with doxorubicin restored body and testes … [48] Doxorubicin caused a lot
of injuries in testes tissue, … Melatonin can decrease non-enzymatic LPO in rat testicular

Protective effect of melatonin on alleviating early oxidative stress induced by DOX in mice spermatogenesis and sperm quality maintaining

T Zi, YN Liu, YS Zhang, ZL Wang, ZX Wang… - Reproductive Biology …, 2022 - Springer
… Many studies have attempted to protect against DOX-induced testicular toxicity, with
mixed results [17, 18]. Melatonin (MLT) is a promising antioxidant agent with a variety of …

Cardioprotective effect of melatonin and agomelatine on doxorubicin-induced cardiotoxicity in a rat model: an electrocardiographic, scintigraphic and biochemical …

H Aygun, SS Gul - Bratislava Medical Journal/Bratislavské …, 2019 - search.ebscohost.com
… demonstrated to protect brain in cerebral ischemia-reperfusion injury and
pentylenetetrazole-induced kindling epilepsy in rats, reduce testicular damage in STZ-induced Type I …

Melatonin as an adjuvant treatment modality with doxorubicin

PM Dana, F Sadoughi, RJ Reiter, S Mohammadi… - Biochimie, 2022 - Elsevier
… of AMPK, abolishes the mentioned effects [57]. In rats treated with melatonin and Dox, cardiac
… MLT suppressed Dox-induced testicular histopathological toxicity but did not reverse the …

[PDF][PDF] Protective effects of melatonin on doxorubicin induced cardiotoxicity in isolated rat heart

ZE Ozgen, M Erdinc, H Akkoc… - Eastern Journal of …, 2016 - jag.journalagent.com
… Oxidative damage is suggested to play a major role … effects of melatonin-which is a free
radical scavenger and antioxidant-on Doxorubicin-induced cardiotoxicity in isolated perfused rat

Effects of quercetin against doxorubicin-induced testicular toxicity in male rats

Ö Güleş, G Doğan, UH Ercins, Ü Eren - Biology Bulletin, 2022 - Springer
… study investigated the protective effects of quercetin (QUE) in doxorubicin (DOX)-induced
to investigate the detailed effects of QUE against DOX-induced testicular toxicity in male rats. …

The role of melatonin on doxorubicin-induced cardiotoxicity: a systematic review

M Najafi, MRH Shayesteh, K Mortezaee, B Farhood… - Life sciences, 2020 - Elsevier
… was reported in the rats treated with doxorubicin compared to the control rats; the survival …
the other rats [14,15]. When both melatonin and doxorubicin was administered to the rats/mice, …