Effectiveness of a comprehensive oral management protocol for the prevention of severe oral mucositis in patients receiving radiotherapy with or without …

Y Kawashita, Y Koyama, H Kurita, M Otsuru… - International Journal of …, 2019 - Elsevier
The aim of this phase II, multicentre, randomized controlled trial was to evaluate the
effectiveness of a comprehensive oral management protocol for the prevention of severe
oral mucositis in patients with oral cancer receiving radiotherapy alone or
chemoradiotherapy. In total, 124 patients with oral cancer were enrolled from five
institutions. Of these, 37 patients undergoing radiotherapy were randomly divided into an
intervention group (n= 18) and a control group (n= 19). The remaining 87 patients, who were …
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