Objective This study investigated the biochemical, histopathological and physiological
effects of Citrullus colocynthis on peripheral neuropathy in rats with streptozotocin (STZ)-
induced diabetes. Methods Seventy adult male Sprague-Dawley rats were included in the
present study. Diabetes was induced in 60 rats, with a single intraperitoneal injection of STZ
(65 mg/kg). After 4 weeks, the diabetic rats were assessed for neuropathy. Then, the diabetic
rats with neuropathy were randomly divided into 6 groups for a 4-week treatment with …