Amiodarone and thyroid physiology, pathophysiology, diagnosis and management

RG Trohman, PS Sharma, EA McAninch… - Trends in cardiovascular …, 2019 - Elsevier
… The effects of amiodarone on thyroid hormone economy are, at … effects of amiodarone/DEA
have been attributed to their ability to decrease thyroid hormone signaling in the myocardium, …

[HTML][HTML] Deiodinases control local cellular and systemic thyroid hormone availability

J Köhrle, C Frädrich - Free Radical Biology and Medicine, 2022 - Elsevier
… Selenium (Se) status has a modest impact on DIO … rT3 and T4 as well as the 5-deiodination
of ITH sulfates such as T3… to PTU in cerebral cortex of hypothyroid rats, the distinct reaction …

Prevalence of amiodarone-induced hypothyroidism; a systematic review and meta-analysis

K Mohammadi, D Shafie, M Vakhshoori… - Trends in …, 2023 - Elsevier
Amiodarone's obligatory effect on the thyroid results in TSH rise due to considerable
possession of iodide in its structure, which ultimately causes a temporary Wolff–Chaikoff effect with …

Thyroid hormones in critical illness

MJ Maiden, DJ Torpy - Critical care clinics, 2019 - criticalcare.theclinics.com
Thyroid hormone has direct effects on the cardiovascular system to increase cardiac output.
This incorporates a direct effect on chronotropy (heart rate), lusitropy (diastolic relaxation), …

Thyroid dysfunction and heart failure: mechanisms and associations

H Vargas-Uricoechea, A Bonelo-Perdomo - Current heart failure reports, 2017 - Springer
tri-iodothyronine (T3). The major pathway for the production of circulating T3 is via 5
deiodination … cardiomyopathy” defines myocardial damage caused by the toxic effects of abundant …

[HTML][HTML] Thyroid function in nonthyroidal illness

DS Ross, DS Cooper, JE Mulder - Cytokines (such as tumor necrosis factor …, 2016 - medilib.ir
TSH concentrations but usually have a normal serum TSH … T3 is produced by the peripheral
5'-deiodination of T4 to T3, a … trial of patients presenting with myocardial infarction, N-…

Occurrence of hypothyroidism in chronic liver disease and corelation of free triidothyronine with child pugh score

M Chandrasekhar - 2018 - repository-tnmgrmu.ac.in
… 110nmol of thyroxine and 10nmol of tri- iodothyronine each … cells, inflammation, myocardial
infarction) in which D3 is upregulated … the 5-deiodination of T4, resulting in generation of rT3. …

Study of Thyroid Function Test in Critically ILL Patients and its Correlation with Apache–II Score

AS Karmakar - 2018 - search.proquest.com
… Gross and Pitt-Rivers found Tri-iodothyronine (T3), a more … Stimulation of D1- and D2-catalyzed
5-deiodination of T4 in … The effects of amiodarone resemble those observed with the …

Prevalence of Thyroid Dysfunction in Alcoholic Liver Cirrhosis and Relation of Serum Free Tri-Iodothyronine with Child Pugh Score

N Praveen - 2019 - search.proquest.com
… Drugs like amiodarone, methotrexate and nitrofurantoin may lead to … TSH. Type III deiodinase
isoform is also found in the central nervous system and catalyzes the 5-deiodination of T4, …

Serum Ghrelin Levels in Hypothyroid Patients

P Sumathi - 2020 - repository-tnmgrmu.ac.in
… of thyroid hormones, triiodothyronine (T3) and thyroxine(T4), to … The cardiac contractile force
is enhanced by the myocardial … with an efficacy order in rats and humans of carbohydrates > …