Distinct patterns of atrial electrical and structural remodeling in angiotensin II mediated atrial fibrillation

HJ Jansen, M Mackasey, M Moghtadaei… - Journal of molecular and …, 2018 - Elsevier
… This study demonstrates that hypertension and elevated Ang II cause distinct patterns of
electrical and structural remodeling in the right and left atria that collectively create a substrate …

Atrial Electrical Remodeling in Mice With Cardiac‐Specific Overexpression of Angiotensin II Type 1 Receptor

J Demers, AT Ton, F Huynh, S Thibault… - Journal of the …, 2022 - Am Heart Assoc
… levels are thought to play an important role in atrial electrical and structural remodeling
receptor antagonists have been shown to reduce the risk of developing AF in patients with …

[HTML][HTML] Pressure-overload-induced angiotensin-mediated early remodeling in mouse heart

JH Kim, YP Jiang, IS Cohen, RZ Lin, RT Mathias - PLoS One, 2017 - journals.plos.org
… the angiotensin II type 1 receptor inhibitor saralasin for 2electrical remodeling occurs and
finally structural remodeling. With regard to the studies presented here, structural remodeling

Angiotensin II and angiotensin 1–7: which is their role in atrial fibrillation?

A Mascolo, K Urbanek, A De Angelis, M Sessa… - Heart failure …, 2020 - Springer
structural and electrical atrial remodeling through the direct infiltration in the atrial myocardium
or through indirect effects … ) and Randomized trial of angiotensin II-receptor blocker vs. …

An N-/L-type calcium channel blocker, cilnidipine, suppresses autonomic, electrical, and structural remodelling associated with atrial fibrillation

K Tajiri, JB Guichard, X Qi, F Xiong… - Cardiovascular …, 2019 - academic.oup.com
… the increase in plasma angiotensin II levels that occur in … electrical remodelling. These
actions contrast with those of the LTCC blocker amlodipine, which increases plasma angiotensin II

Angiotensin II Receptor Blockers and Arrhythmias in Ventricular Hypertrophy

G Salama - Journal of the American Heart Association, 2022 - Am Heart Assoc
… first AT 1 R (angiotensin II [Ang II] type 1 receptor) blocker or … direct effect on ion channel
remodeling or indirect effects through … /ventricular fibrillation induced by electrical stimulation. All …

Protease-activated receptor 1 contributes to angiotensin II-induced cardiovascular remodeling and inflammation

S Antoniak, JC Cardenas, LJ Buczek, FC Church… - Cardiology, 2017 - karger.com
… data indicate that PAR-1 plays a significant role in cardiovascular remodeling mediated by a
… Most of the effects of Ang II are mediated by angiotensin type 1 (AT 1 ) receptors [1,2]. While …

Sacubitril/valsartan attenuates atrial electrical and structural remodelling in a rabbit model of atrial fibrillation

Q Lou, G Liu, J Lv, F Yun, T Li, W Yang, H Zhao… - European journal of …, 2020 - Elsevier
… Sacubitril/valsartan, an angiotensin receptor–neprilysin inhibitor (ARNi), consists of the … of
valsartan (angiotensin II type 1 receptor blocker-ARB) and sacubitril (the neprilysin inhibitor) (…

High hydrostatic pressure induces atrial electrical remodeling through angiotensin upregulation mediating FAK/Src pathway activation

X Li, CY Deng, YM Xue, H Yang, W Wei, FZ Liu… - Journal of Molecular and …, 2020 - Elsevier
… inhibited by angiotensin type 1 receptor inhibitor valsartan, … of atrial electrical and structural
remodeling and contributes to … -angiotensin system (RAS), especially angiotensin II (Ang II)-…

[HTML][HTML] Effects of trandolapril on structural, contractile and electrophysiological remodeling in experimental volume overload heart failure

D Jarkovská, M Miklovič, J Švíglerová… - Frontiers in …, 2021 - frontiersin.org
… Effective suppression of electrical proarrhythmic remodeling and … such as ACE inhibitors,
angiotensin receptor blockers and … effects are based on decreased levels of angiotensin II, …