… triphosphate–dependent drug efflux pump, will reduce net transfer … for accurate
pharmacokineticpharmacodynamic modeling. … , ethanol) are readily transferred into breast milk. …

… The need to pump breast milk to either discard or store for later … Table 1-1 lists the
pharmacokinetic properties of these agents, … Ethanol is highly lipid soluble and small in size, with …

… exposure to the infant via breast milk, and the specific drug … drugs available for
pharmacodynamic effect in the mother but … the effects of protein binding, ionization, and efflux …

… eg neurotoxicity of ethanol hypothyroidism-related cretinism … These protein pumps have
been postulated to have evolved … of using maternal medications during breastfeeding is dual. …

… In the seventh, titled Maternal Considerations, we review how the drug impacts … breastfeeding,
but there is reasonable doubt of safety, we will recommend the patient pump her breasts …

… be used to evaluate pharmacokinetic parameters in maternal … moderate amounts of ethanol
during pregnancy might suffer … Several mechanisms underlying the effects of ethanol on the …

… of medications fall into 2 categories: maternal pharmacokinetic changes during lactation …
A complete 24-h milk collection from both breasts using an electric breast pump for each milk …

… breast milk; how to evaluate the infant's risk from breast milk … Fortunately, multiple
pharmacokinetic scenarios prohibit … with lactating patients, so that breastfeeding or pumping …

… As ethanol is water-soluble, it enters the milk rapidly through … to affect women’s alcohol
pharmacokinetics, and thus is likely … the effect of breast pumping on alcohol in human milk. In a …

… and disease state; ethanol based liquid formulations have up to … biliary efflux pumps (P-gp,
and Breast cancer resistance protein … , presumably through exposure from maternal milk [31]. …