Vascular cognitive impairment

M Dichgans, D Leys - Circulation research, 2017 - Am Heart Assoc
… imaging evidence of cerebrovascular disease and should be … burden of subcortical ischemic
lesions and lower cognitive … identifying individuals at risk for developing cognitive decline

Cerebrovascular resistance: effects on cognitive decline, cortical atrophy, and progression to dementia

…, Alzheimer's Disease Neuroimaging Initiative - Brain, 2017 - academic.oup.com
… was associated with accelerated decline in global cognition, … in cerebrovascular resistance
we observed in individuals with higher … burden on cortical atrophy and cognitive decline, and …

The role of cerebrovascular disease in amyloid deposition

Y Noh, SW Seo, S Jeon, JM Lee, JS Kim… - … Disease, 2016 - content.iospress.com
amyloid burden between SVCI and Alzheimer’s disease type … As controls, we included 13
participants with normal cognition … no subjects who met the clinical criteria for cerebral amyloid

Vascular cognitive impairment

WM Van Der Flier, I Skoog, JA Schneider… - … Reviews Disease …, 2018 - nature.com
… due to cerebrovascular disease seems to decline at very old … in individuals with other
subcortical vascular diseases such … with a subcortical location might also affect cognition 61 . …

Assessment of extent and role of tau in subcortical vascular cognitive impairment using 18F-AV1451 positron emission tomography imaging

HJ Kim, S Park, H Cho, YK Jang, J San Lee… - JAMA …, 2018 - jamanetwork.com
… structural changes or cognition. Thus, CSVD and Aβ leading to … Normal control individuals
were all characterized by the … included patients with significant vascular burden, which may …

[HTML][HTML] Distinctive mediating effects of subcortical structure changes on the relationships between amyloid or vascular changes and cognitive decline

NY Jung, JH Shin, HJ Kim, H Jang, SH Moon… - Frontiers in …, 2021 - frontiersin.org
… stage between normal cognition and several types of … The amyloid beta (Aβ) burden is a
characteristic pathologic … mesh surfaces were extracted from the labeled images for each subject

Tau mediates synergistic influence of vascular risk and Aβ on cognitive decline

WYW Yau, Z Shirzadi, HS Yang, AP Ikoba… - Annals of …, 2022 - Wiley Online Library
… Our primary measure of cardiovascular disease risk was the … on cognitive decline in individuals
with elevated Aβ burden. In … vascular risk, given its modifying effect on tau and cognition. …

Association of Glycemic Variability With Imaging Markers of Vascular Burden, β-Amyloid, Brain Atrophy, and Cognitive Impairment

H Jang, S Lee, S An, Y Park, SJ Kim, BK Cheon… - Neurology, 2024 - AAN Enterprises
… and cognition in a cohort of individuals without dementia. Our findings indicate that GV may
be considered a potential modifiable risk factor in the prevention of cognitive impairment and …

[HTML][HTML] Protective effects of APOE e2 against disease progression in subcortical vascular mild cognitive impairment patients: A three-year longitudinal study

YJ Kim, SW Seo, SB Park, JJ Yang, JS Lee, J Lee… - Scientific reports, 2017 - nature.com
… of corresponding regions among the subjects, the thicknesses were … apoE isoform-specific
disruption of amyloid beta peptide … Journal of stroke and cerebrovascular diseases: the official …

Vascular burden and cognition: Mediating roles of neurodegeneration and amyloid PET

, … (MITNEC) and Alzheimer's Disease … - Alzheimer's & …, 2023 - Wiley Online Library
… what extent cerebrovascular burden relates to amyloid beta (… subjects, we investigated the
association of vascular burden (… that the WMH effects on cognitive impairment may be mainly …