Blood–brain barrier link to human cognitive impairment and Alzheimer's disease
… with amyloid beta and tau AD biomarkers to confer cognitive … breakdown in individuals with
early cognitive impairment, … not influenced by vascular risk factor (VRF) burden 24,35 . As …
early cognitive impairment, … not influenced by vascular risk factor (VRF) burden 24,35 . As …
Functional trajectories, cognition, and subclinical cerebrovascular disease
… of penetrating arteries, subcortical but likely embolic infarcts were … For individuals with no
cognitive impairment at baseline (… Finally, the BI is subject to ceiling effects, and we may have …
cognitive impairment at baseline (… Finally, the BI is subject to ceiling effects, and we may have …
Emerging role of vascular burden in AT (N) classification in individuals with Alzheimer's and concomitant cerebrovascular burdens
MY Chun, H Jang, SJ Kim, YH Park, J Yun… - Journal of Neurology …, 2024 - jnnp.bmj.com
… on longitudinal cognition changes in V– and V+ groups. A, β-… the V burden affected the
cognitive decline trajectories across the … . Clinical significance of amyloid beta positivity in patients …
cognitive decline trajectories across the … . Clinical significance of amyloid beta positivity in patients …
Microbleeds in fronto-subcortical circuits are predictive of dementia conversion in patients with vascular cognitive impairment but no dementia
YK Chen, WM Xiao, W Li, ZX Ni, YL Liu… - Neural Regeneration …, 2018 - journals.lww.com
… to cognitive impairment. However, the association between CMBs and dementia conversion
in individuals … Therefore, we hypothesized that the presence of CMBs in specific cognition-…
in individuals … Therefore, we hypothesized that the presence of CMBs in specific cognition-…
[HTML][HTML] Novel imaging techniques in cerebral small vessel diseases and vascular cognitive impairment
… of cerebrovascular disease, including cortical and subcortical … Despite the economic burden
of dementia being almost twice … (33% weighted average), as well as older subjects without …
of dementia being almost twice … (33% weighted average), as well as older subjects without …
Interactions between vascular burden and amyloid-β pathology on trajectories of tau accumulation
EM Coomans, D van Westen, AP Binette, O Strandberg… - Brain, 2024 - academic.oup.com
… unimpaired individuals, we further found that stroke-related … cardiovascular or cerebrovascular
disease may have a better … with and without cognitive impairment from the Swedish …
disease may have a better … with and without cognitive impairment from the Swedish …
Neuroimaging in vascular cognitive impairment: a state-of-the-art review
WD Heiss, GA Rosenberg, A Thiel, R Berlot… - BMC medicine, 2016 - Springer
… are seen prior to those in cognition. This review describes the … , rather than caused by
cerebrovascular disease [35]. Superficial … ratio in subjects with mild cognitive impairment (MCI) …
cerebrovascular disease [35]. Superficial … ratio in subjects with mild cognitive impairment (MCI) …
The contribution of vascular risk factors in neurodegenerative disorders: From mild cognitive impairment to Alzheimer's disease
YW Cheng, MJ Chiu, YF Chen, TW Cheng… - Alzheimer's research & …, 2020 - Springer
… in subjects with MCI and low cerebral SVD burden, vascular … enriched for cerebrovascular
disease and vascular risk factors. … cognition through its lipid-lowering effect or other pleotropic …
disease and vascular risk factors. … cognition through its lipid-lowering effect or other pleotropic …
Association of cerebral small vessel disease and cognitive decline after intracerebral hemorrhage
… effect sizes for association with cognition after ICH across all … Our study cohort also comprised
individuals presenting to a … CSVD burden suggest that post-ICH cognitive impairment is …
individuals presenting to a … CSVD burden suggest that post-ICH cognitive impairment is …
Aβ (amyloid beta) and tau tangle pathology modifies the association between small vessel disease and cortical microinfarcts
… , to overall brain health, cognition, and dementia. Microinfarcts … a large sample of autopsied
individuals, which allows us to … -tau tangle burden from 8 brain regions, and multiple vascular …
individuals, which allows us to … -tau tangle burden from 8 brain regions, and multiple vascular …