The effect of prolonged simvastatin application on serotonin uptake, membrane microviscosity and behavioral changes in the animal model
J Vevera, K Valeš, Z Fišar, J Hroudová, N Singh… - Physiology & …, 2016 - Elsevier
… ie the hippocampus, striatum and frontal cortex. Also, a link between impairment of serotonin
… of sertraline, also a selective serotonin reuptake inhibitor, but did not change the effect of …
… of sertraline, also a selective serotonin reuptake inhibitor, but did not change the effect of …
[HTML][HTML] Antioxidant effect of simvastatin throught oxidative imbalance caused by lisdexamfetamine dimesylate
GA Eger, VV Ferreira, CR Batista, H Bonde… - Anais da Academia …, 2016 - SciELO Brasil
… Effects of high dose of simvastatin on levels of dopamine and its reuptake in prefrontal cortex
and striatum among SD rats. … in which simvastatin upregulated NMDAR in the rat brain, and …
and striatum among SD rats. … in which simvastatin upregulated NMDAR in the rat brain, and …
[HTML][HTML] The effect of atorvastatin on obsessive-compulsive symptoms of refractory obsessive-compulsive disorder (add-on therapy)
S Akouchekian, V Omranifard, P Moshfegh… - Advanced Biomedical …, 2018 - journals.lww.com
… guides, selective serotonin reuptake inhibitors (SSRIs) and … prefrontal cortex with potential
mechanisms of endothelial nitric oxide synthase. The results of this study suggest that statins …
mechanisms of endothelial nitric oxide synthase. The results of this study suggest that statins …
Effects of statins on dopamine loss and prognosis in Parkinson's disease
… total cholesterol level mediated the associations between statin use … to be associated with
cholesterol level, were entered as … statin increases striatal dopamine content without affecting …
cholesterol level, were entered as … statin increases striatal dopamine content without affecting …
Update on statin treatment in patients with neuropsychiatric disorders
… administration of a selective serotonin reuptake-inhibitor (SSRI) [… association between
anxiety and non-adherence to statins … dopamine concentrations in the prefrontal cortex [114,115]. …
anxiety and non-adherence to statins … dopamine concentrations in the prefrontal cortex [114,115]. …
Statins and the brain: more than lipid lowering agents?
A Fracassi, M Marangoni, P Rosso… - Current …, 2019 - ingentaconnect.com
… indicates that the relationship between statins and PD is not … regions and by the release
of striatal dopamine [255]. Cruz … in the hippocampus and prefrontal cortex, two brain regions …
of striatal dopamine [255]. Cruz … in the hippocampus and prefrontal cortex, two brain regions …
The Potential Therapeutic Application of Simvastatin for Brain Complications and Mechanisms of Action
YM Vuu, A Kadar Shahib, M Rastegar - Pharmaceuticals, 2023 - mdpi.com
… , amongst its two groups, lipophilic statins have a higher ability … of simvastatin for 4 weeks in
Sprague–Dawley rats restored … significantly increased dopamine content in the striatum [168]…
Sprague–Dawley rats restored … significantly increased dopamine content in the striatum [168]…
Rosuvastatin improves olanzapine's effects on behavioral impairment and hippocampal, hepatic and metabolic damages in isolated reared male rats
A Mohammed, WM El-Bakly, A Ali… - Behavioural Brain …, 2020 - Elsevier
… such as serotonin (5-HT) and dopamine (DA), and dysfunction of these … In addition, statins
showed neuroprotective effects in … changes among all of the groups where: A and B, SR rats, …
showed neuroprotective effects in … changes among all of the groups where: A and B, SR rats, …
Effect of selective serotonin reuptake inhibitor on prefrontal-striatal connectivity is dependent on the level of TNF-α in patients with major depressive disorder
K Liu, X Zhao, X Lu, X Zhu, H Chen, M Wang… - Psychological …, 2019 - cambridge.org
… level in MDD patients. In another word, the extent of FC decrease between striatum and
prefrontal cortices after SSRI treatment was less significant in MDD individuals with a high level …
prefrontal cortices after SSRI treatment was less significant in MDD individuals with a high level …
Effects of simvastatin beyond dyslipidemia: Exploring its antinociceptive action in an animal model of complex regional pain syndrome-type I
G Vieira, J Cavalli, ECD Gonçalves… - Frontiers in …, 2017 - frontiersin.org
… There are some evidences exploring the relation between simvastatin and its central
effects, such as: (i) altering dopamine D1 and D2 receptors, Wang et al. (2005, 2006); (ii) …
effects, such as: (i) altering dopamine D1 and D2 receptors, Wang et al. (2005, 2006); (ii) …