Chronic ethanol drinking increases during the luteal menstrual cycle phase in rhesus monkeys: implication of progesterone and related neurosteroids
BL Dozier, CA Stull, EJ Baker, MM Ford, JP Jensen… - …, 2019 - Springer
… to other phases of the menstrual cycle, this study did not measure sex hormones to confirm
… Additional pharmacokinetic studies where menstrual cycle phase was confirmed by sex …
… Additional pharmacokinetic studies where menstrual cycle phase was confirmed by sex …
Modeling corticosteroid pharmacokinetics and pharmacodynamics, part II: sex differences in methylprednisolone pharmacokinetics and corticosterone suppression
… differences in steroid responses. This report … pharmacokinetics of MPL and its adrenal
suppressive effects. Because time-dependent (estrous) regulation of sex hormones in females can …
suppressive effects. Because time-dependent (estrous) regulation of sex hormones in females can …
Influence of age and sex on alcohol pharmacokinetics and subjective pharmacodynamic responses following intravenous alcohol exposure in humans
V Vatsalya, ND Byrd, BL Stangl, R Momenan… - Alcohol, 2023 - Elsevier
… Young females had normal menstrual cycles, were tested during … pharmacokinetics and
pharmacodynamics of alcohol. The older individuals are thought to be more sensitive to alcohol …
pharmacodynamics of alcohol. The older individuals are thought to be more sensitive to alcohol …
Sex-related differences in pharmacokinetics and pharmacodynamics of frequently prescribed drugs: a review of the literature
A Farkouh, T Riedl, R Gottardi, M Czejka… - Advances in …, 2020 - Springer
… While the normal menstrual cycle has no clinically relevant effect … of ethanol in women and
represents the underlying … , that the female physiological sex hormones in the first half of the …
represents the underlying … , that the female physiological sex hormones in the first half of the …
Sexual dimorphism in drug metabolism and pharmacokinetics
AM Valodara, KJ SR - Current Drug Metabolism, 2019 - ingentaconnect.com
… of female sex hormones is influenced by the menstrual cycle, pregnancy and breastfeeding
[9]. Women, due to their phases of the menstrual cycle, … One such enzyme is gastric alcohol …
[9]. Women, due to their phases of the menstrual cycle, … One such enzyme is gastric alcohol …
Sex impact on biomarkers, pharmacokinetics and pharmacodynamics
F Franconi, I Campesi - Current medicinal chemistry, 2017 - ingentaconnect.com
… sexual hormones may influence all pharmacokinetic processes [9, 10, 42, 52]. As concentrations
of sexual hormones change throughout a woman’s … During the menstrual cycle, pharma…
of sexual hormones change throughout a woman’s … During the menstrual cycle, pharma…
The pharmacodynamic effects of combined administration of flibanserin and alcohol
DM Stevens, JM Weems, L Brown… - Journal of Clinical …, 2017 - Wiley Online Library
… females 21-55 years of age with regular menstrual cycles, … of moderate alcohol intake (approximately
5-21 units of alcohol/… pharmacodynamic rather than pharmacokinetic in nature. …
5-21 units of alcohol/… pharmacodynamic rather than pharmacokinetic in nature. …
Sex differences in alcohol use disorder
… explained by the sex differences observed in the pharmacokinetics of alcohol. Women also
show an … It is not clear whether alcohol absorption also changes with menstrual cycle [44]. …
show an … It is not clear whether alcohol absorption also changes with menstrual cycle [44]. …
Effect of menstrual cycle on ethanol drinking in rhesus monkeys
SG Thomas, PW Czoty - Drug and alcohol dependence, 2019 - Elsevier
… between menstrual cycle phase and intake of ethanol (EtOH) in five adult female rhesus
monkeys. … Menstrual cycle was determined with vaginal swabs 5–7 days per week. To facilitate …
monkeys. … Menstrual cycle was determined with vaginal swabs 5–7 days per week. To facilitate …
Sex differences in the acute ethanol effects on object recognition memory: influence of estrous cycle
MA Paiva-Santos, AHFF Leão, JPF Kurita… - Behavioural …, 2022 - journals.lww.com
… sex hormones. The aim of this study was to investigate the influence of sex and estrous cycle
in the acute effects … Male and female Wistar rats were part of one of the groups: control, 0.6-g…
in the acute effects … Male and female Wistar rats were part of one of the groups: control, 0.6-g…