Vascular calcification maladaptively participates in acute phosphate homeostasis

ME Turner, TS Rowsell, AP Lansing… - Cardiovascular …, 2023 - academic.oup.com
chronic kidney disease (CKD), where exposure to increased … and phosphate binder therapy
is prevalent in CKD patients, … have shown its most dramatic effect is on the progression of pre…

Nicotinamide and phosphate homeostasis in chronic kidney disease

C Ginsberg, JH Ix - Current opinion in nephrology and …, 2016 - journals.lww.com
… Although phosphate binders are commonly used to lower phosphate, they are minimally …
Effects of phosphate binder therapy on vascular stiffness in early-stage chronic kidney disease

Effect of ferric citrate hydrate on FGF23 and PTH levels in patients with non-dialysis-dependent chronic kidney disease with normophosphatemia and iron deficiency

A Iguchi, S Yamamoto, M Yamazaki, K Tasaki… - Clinical and …, 2018 - Springer
… We hypothesized that ferric citrate hydrate, an iron-based phosphate binder, will decrease …
Effects of phosphate binder therapy on vascular stiffness in early-stage chronic kidney disease

Chronic Kidney Disease–Mineral and Bone Disorders

IA Portales-Castillo, EW Yu, H Jüppner… - … Chronic Kidney Disease …, 2022 - Springer
… explaining why even patients with early-stage CKD have lower … -containing binders,
especially in patients with elevated … -target effects and costs of specific phosphate binders should …

[HTML][HTML] Reduced Levels of the Antiaging Hormone Klotho are Associated With Increased Aortic Stiffness in Diabetic Kidney Disease

N Fountoulakis, PM Psefteli, G Maltese, L Gnudi… - Kidney International …, 2023 - Elsevier
… In the early stages of chronic kidney disease (CKD), there is … were no patients receiving
vitamin D, phosphate binders, or … In our cohort in people with diabetes and early stage CKD the …

[HTML][HTML] … of dietary phosphate intake with risk of end-stage renal disease and mortality in chronic kidney disease stages 3–5: The Modification of Diet in Renal Disease …

U Selamet, H Tighiouart, MJ Sarnak, G Beck… - Kidney international, 2016 - Elsevier
… KDIGO recommended the use of intestinal phosphate binders and limiting dietary phosphate
… data demonstrating the effects of alterations in intestinal phosphate absorption on serum …

[HTML][HTML] Diagnosis and Management of Chronic Kidney Disease-Mineral Bone Disease in Children

JS Suh - Childhood Kidney Diseases, 2020 - chikd.org
Patients with early-stage CKD who present with disordered … increased to monitor treatment
efficacy and side effects. The … Phosphate binders in combination with dietary phosphorus

Chronic kidney disease-mineral and bone disorder: Guidelines for diagnosis, treatment, and management

C Moschella - Jaapa, 2016 - journals.lww.com
… become clinically detectable until late stage 3 or early stage 4. … whom the effect of treatment
on bone needs to be assessed.” … of dietary phosphate restriction and phosphate binders, with …

[HTML][HTML] … in the chronic kidney disease-mineral bone disorder show the role of osteocytic proteins, a potential mechanism of the bone—Vascular paradox, a therapeutic …

MJ Williams, SC White, Z Joseph, KA Hruska - Frontiers in Physiology, 2023 - frontiersin.org
… is an early stage of cardiovascular disease leading to high … been implicated in vascular
calcification, although the effects are … use of calcium-containing phosphate binders, can result in …

Bone and mineral disorders in chronic kidney disease: implications for cardiovascular health and ageing in the general population

A Covic, M Vervloet, ZA Massy, PU Torres… - The lancet Diabetes & …, 2018 - thelancet.com
… The patient with chronic kidney disease (CKD) represents an … risk factors have effects on
outcomes. But CKD can also be viewed … binders or blockers of intestinal phosphate transport. …