Abstract Ethnopharmacologic relevance Lavandula angustifolia Mill (lavender) odor was
traditionally used as sleep enhancer. Previous studies have shown interaction between
insomnia, quality of life and control of diabetes mellitus (DM). Insomnia is suggested to
increase the risk of depression and decrease the quality of life in diabetic patients. The aim
of this study was to evaluate the efficacy of inhaled Lavandula angustifolia Mill. as a
complementary therapy for insomnia in diabetic patients. Methods In a randomized …

Methods In a randomized crossover placebo-controlled clinical trial, 52 patients with type II
diabetes mellitus (DM) and insomnia, defined as Pittsburgh Insomnia Rating Scale-20 (PIRS-
20)> 5, were treated with inhaled lavender or placebo for two periods of 4 weeks duration
with one week interval as washing period. Sleep quality, quality of life and mood status were
assessed by PIRS-20, WHO Quality of Life-BREF (WHOQOL-BREF) Questionnaire and Beck
Depression Inventory (BDI) scale respectively, at baseline and end of each period of study …