Molecular mechanisms of Cisplatin-induced placental toxicity and teratogenicity in rats and the ameliorating role of N-acetyl-cysteine
MS Hassan, AM Morgan, MM Mekawy… - The International Journal …, 2019 - Elsevier
… High levels of Cisplatin-DNA adducts have previously been … in mitochondrial DNA (mtDNA)
from organs of pregnant rats, … liver mitochondria of fetal rats exposed transplacentally and …
from organs of pregnant rats, … liver mitochondria of fetal rats exposed transplacentally and …
Teratogenic effect of cisplatin in rats and the protective role of sodium selenate
… in the elevated morphological abnormalities compared to cisplatin − … of the mitochondrial
signaling pathway in this process. … to transplacental transfer of cisplatin from mother to the fetus …
signaling pathway in this process. … to transplacental transfer of cisplatin from mother to the fetus …
[PDF][PDF] Protective effect of chrysin against cisplatin induced pulmonary toxicity in wister rats
MO Oladipo, S Sultana, AS Saganuwan, HC Nwanko - WCRJ, 2023 - wcrj.net
… The isolated genomic DNA of lung tissues in this study, by the gel electrophoresis showed …
Elevated mitochondrial cisplatin- DNA adduct levels in rat tissues after transplacental cisplatin …
Elevated mitochondrial cisplatin- DNA adduct levels in rat tissues after transplacental cisplatin …
Magnesium Isoglycyrrhizinate Reduces the Target-Binding Amount of Cisplatin to Mitochondrial DNA and Renal Injury through SIRT3
X Wang, H Zhu, J Hu, H Li, S Guo, B Chen… - International Journal of …, 2022 - mdpi.com
… cisplatin-DNA binding levels in liver and brain mitochondrial … In the kidney tissue of
cisplatin-induced renal injury mouse … the level of SIRT3, thus reducing mtDNA adduct levels and …
cisplatin-induced renal injury mouse … the level of SIRT3, thus reducing mtDNA adduct levels and …
[PDF][PDF] Platinum analogues
L Amable, E Reed, BA Chabner - … , Immunotherapy and Biotherapy, 2019 - academia.edu
… As previously discussed, NER is responsible for the repair of cisplatin-DNA adduct, and …
Elevated mitochondrial cisplatin-DNA adduct levels in rat tissues after transplacental cisplatin …
Elevated mitochondrial cisplatin-DNA adduct levels in rat tissues after transplacental cisplatin …
Protective effects of ACY-1215 against chemotherapy-related cognitive impairment and brain damage in mice
D Wang, B Wang, Y Liu, X Dong, Y Su, S Li - Neurochemical Research, 2019 - Springer
… deficits and dendritic spine loss and increased synaptic density in cisplatin-treated mice. …
the levels of cisplatin-mtDNA adducts are much higher than that of cisplatin-nDNA adducts. …
the levels of cisplatin-mtDNA adducts are much higher than that of cisplatin-nDNA adducts. …
Indole-3-carbinol protects against cisplatin-induced acute nephrotoxicity: role of calcitonin gene-related peptide and insulin-like growth factor-1
RN El-Naga, YF Mahran - Scientific reports, 2016 - nature.com
… against cisplatin-induced acute nephrotoxicity in rats? (2) If so… -α inhibitors increased the
survival of mice given cisplatin by … , cisplatin injection significantly increased tissue levels of pro-…
survival of mice given cisplatin by … , cisplatin injection significantly increased tissue levels of pro-…
Cisplatin-induced nephrotoxicity in children: what is the best protective strategy?
A Ruggiero, A Ariano, S Triarico… - Journal of Oncology …, 2021 - journals.sagepub.com
… Cisplatin–DNA adducts [N-7 adducts at d(GpC) and d(ApG)] … associated with the increased
number of mitochondria, which … , cisplatin-related damage to nuclear and mitochondrial DNA …
number of mitochondria, which … , cisplatin-related damage to nuclear and mitochondrial DNA …
Chemotherapeutic-induced cardiovascular dysfunction: physiological effects, early detection—the role of telomerase to counteract mitochondrial defects and oxidative …
N Quryshi, LE Norwood Toro, K Ait-Aissa… - International journal of …, 2018 - mdpi.com
… the claim that TRPV1 is responsible for the cisplatin mediated Ca 2+ increase [100,104]. …
In two studies, cisplatin adducts were found to reside within the mt DNA of fetal tissues of rat …
In two studies, cisplatin adducts were found to reside within the mt DNA of fetal tissues of rat …
[HTML][HTML] Upregulated SLC22A3 has a potential for improving survival of patients with head and neck squamous cell carcinoma receiving cisplatin treatment
CM Hsu, PM Lin, JG Chang, HC Lin, SH Li, SF Lin… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… The cisplatin–DNA adduct level is the most critical … or biopsied tissues to predict the response
to and outcome of cisplatin … of the mitochondrial conversion of MTT into formazine. In brief, …
to and outcome of cisplatin … of the mitochondrial conversion of MTT into formazine. In brief, …