Detection of Naja atra Cardiotoxin Using Adenosine-Based Molecular Beacon

YJ Shi, YJ Chen, WP Hu, LS Chang - Toxins, 2017 - mdpi.com
… was conducted by titrating FAM solution with CTX3. CTX3 did not … to cardiotoxin analogue
II from the Taiwan cobra venom (NajaElucidation of the structural interactions in the dATP-…

DNA aptamers against Taiwan banded krait α-bungarotoxin recognize Taiwan cobra cardiotoxins

YJ Chen, CY Tsai, WP Hu, LS Chang - Toxins, 2016 - mdpi.com
… α-Bgt and Naja atra (Taiwan cobra) cardiotoxin 3 (CTX3) … was conducted by titrating a FAM
solution with CTX3 or α-Bgt. … been conducted to elucidate the structure-function relationship …

… of Immunoreactive Peptides of Toxins to Simultaneously Assess the Neutralization Potency of Antivenoms against Neurotoxicity and Cytotoxicity of Naja atra Venom

BS Liu, WG Wu, MH Lin, CH Li, BR Jiang, SC Wu… - Toxins, 2017 - mdpi.com
… (sNTX) and cytotoxicity of cardiotoxin/cytotoxin (CTX), … , respectively, of snake envenomings
in Taiwan and China annually [1,… that treatment of CTX analogs would induce cell mortality in …

Comparison of the primary structures, cytotoxicities, and affinities to phospholipids of five kinds of cytotoxins from the venom of Indian cobra, Naja naja

M Suzuki-Matsubara, SBP Athauda, Y Suzuki… - … and Physiology Part C …, 2016 - Elsevier
… processes of cobra cytotoxins (CTXs) is not yet fully elucidated. … used for the cloning of
cardiotoxin 4 and cobrotoxin of N. … Each CTX solution was added to each well of a 96-well plate, …

Development of a broad-spectrum antiserum against cobra venoms using recombinant three-finger toxins

BS Liu, BR Jiang, KC Hu, CH Liu, WC Hsieh, MH Lin… - Toxins, 2021 - mdpi.com
… chain α-neurotoxins (P60770), and cardiotoxin A3 (P60301) to … Taiwan cobra (Naja atra),
and the Thai spitting cobra (Naja … other CTX analogous in the venoms of cobra snake species. It …

Effects of Cobra Cardiotoxins on Intracellular Calcium and the Contracture of Rat Cardiomyocytes Depend on Their Structural Types

AS Averin, AV Berezhnov, OY Pimenov… - International Journal of …, 2023 - mdpi.com
… Depending on the structure of the N-terminal or the central … was observed for Naja oxiana
cobra cardiotoxin 2, which is of … ’ balanced salt solution (HBSS) with the following composition (…

Current insights in the mechanisms of cobra venom cytotoxins and their complexes in inducing toxicity: implications in antivenom therapy

B Kalita, YN Utkin, AK Mukherjee - Toxins, 2022 - mdpi.com
… across different Naja species; it was ~13% in Taiwanese N. … It should be noted that the
cardiotoxic activity of cobra venom, … Therefore, it remains to be elucidated as to whether or not the …

Snake venom toxins: toxicity and medicinal applications

YS Chan, RCF Cheung, L Xia, JH Wong, TB Ng… - Applied microbiology …, 2016 - Springer
… This enables elucidation of molecular entities contributing to their … naja atra (Taiwan
cobra) cardiotoxin 3 permeabilizes … [Lys(52)]CTX-I(41–60), the truncated cardiotoxin I analog, …

Structural and Dynamic “Portraits” of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?

PV Dubovskii, MA Dubinnyi, AG Konshina… - Biochemistry, 2017 - ACS Publications
… equivalence to the native analogues remains unanswered. … rigid recombinant cardiotoxin
I (CTI) from cobra Naja oxiana … elucidating the conformational abilities of the loop II structure

Monitoring the disulfide bonds of folding isomers of synthetic CTX A3 polypeptide using MS-based technology

SY Huang, TY Wei, BS Liu, MH Lin, SK Chiang… - Toxins, 2019 - mdpi.com
… isomers during the folding reaction of synthetic cardiotoxin … of an investigation on the CTX
analog III, in which NMR … atra) was acquired from a snake farm (Tainan, Taiwan), and the CTX …