Nondopaminergic treatments for Parkinson's disease: current and future prospects

ME Freitas, SH Fox - Neurodegenerative disease management, 2016 - Future Medicine
Parkinson's disease is primarily caused by dysfunction of dopaminergic neurons, however,
nondopaminergic (ND) systems are also involved. ND targets are potentially useful to reduce …

Parkinson's disease: Current drug therapy and unraveling the prospects of nanoparticles

A Paul, KS Yadav - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
… in medical history for James Parkinson's by addition of more symptoms to … Parkinson's
disease (PD) for those symptoms [4]. Being the second most familiar ND after Alzheimer's disease

[HTML][HTML] Newly approved and investigational drugs for motor symptom control in Parkinson's disease

DG Di Luca, NGD Reyes, SH Fox - Drugs, 2022 - Springer
… Here, we review the existing and emerging interventions for PD with focus on newly approved
and investigational drugs for motor symptoms, motor fluctuations, dyskinesia, and balance …

[HTML][HTML] Parkinson's disease drug therapies in the clinical trial pipeline: 2020

K McFarthing, S Buff, G Rafaloff… - … Parkinson's disease, 2020 - content.iospress.com
Background: The majority of current pharmacological treatments for Parkinson’s disease (PD)
were approved for clinical use in the second half of the last century and they only provide …

Insight into the emerging role of striatal neurotransmitters in the pathophysiology of Parkinson's disease and Huntington's disease: a review

S Jamwal, P Kumar - Current neuropharmacology, 2019 - ingentaconnect.com
… Movement disorders like Parkinson disease (PD) and Huntington disease (HD) rank among
… complex group of neurological illness or diseases that manifest either increase or decrease …

[HTML][HTML] Parkinson's disease drug therapies in the clinical trial pipeline: 2021 update

K McFarthing, G Rafaloff, MAS Baptista… - … Parkinson's disease, 2021 - content.iospress.com
… Our hope is that this report will provide some insights into the different approaches to
target PD and explore emerging novel treatment options. We also aim to raise awareness …

Cancer and parkinson's disease: Common targets, emerging hopes

PS Filippou, TF Outeiro - Movement Disorders, 2021 - Wiley Online Library
… of neurodegenerative diseases and … diseases, like Parkinson's disease (PD). We believe
that deciphering the molecular processes and pathways underlying one of these diseases may …

[PDF][PDF] Liposomes: An emerging carrier for targeting Alzheimer's and Parkinson's diseases

SRK Pandian, KK Vijayakumar, S Murugesan… - Heliyon, 2022 - cell.com
… are Alzheimer's disease (AD), Parkinson's disease (PD), dementia, brain cancer, seizures,
mental disorders, and other movement disorders. The major barrier in treating CNS disease is …

Emerging insights between gut microbiome dysbiosis and Parkinson's disease: Pathogenic and clinical relevance

M Bi, L Feng, J He, C Liu, Y Wang, H Jiang… - Ageing Research …, 2022 - Elsevier
Parkinson’s disease (PD) is a complicated neurodegenerative disease, of which gastrointestinal
disturbance appears prior to motor symptoms. Numerous studies have shed light on the …

[HTML][HTML] Emerging preclinical pharmacological targets for Parkinson's disease

SV More, DK Choi - Oncotarget, 2016 - ncbi.nlm.nih.gov
… In the following section, we will discuss some emerging pharmacological PD targets with
substantial preclinical evidence (as also depicted in Table ​1) that can be further considered …