Versatility of cell-penetrating peptides for intracellular delivery of siRNA
… of stable nanoparticles for … that the conjugates might be internalized into the cells via multiple
pathways including direct internalization and clathrin- and caveolae-independent endocytic …
pathways including direct internalization and clathrin- and caveolae-independent endocytic …
Tumor penetrating peptides for improved drug delivery
E Ruoslahti - Advanced drug delivery reviews, 2017 - Elsevier
… These peptides activate an endocytic transport pathway … small molecule drugs to nanoparticles.
The CendR technology … of compounds that are not conjugated to the peptide (by-stander …
The CendR technology … of compounds that are not conjugated to the peptide (by-stander …
Understanding cell penetration of cyclic peptides
… amides in the less permeable peptide were involved in … (including peptides, proteins,
nucleic acids, and nanoparticles… In this section, we will discuss the mechanisms of endocytic …
nucleic acids, and nanoparticles… In this section, we will discuss the mechanisms of endocytic …
Functional moieties for intracellular traffic of nanomaterials
… of those bioactive molecules to intracellular sites, one being based on nanotechnology-…
-conjugated PEI was internalized by caveolae-mediated endocytosis in HEK293T cells, thus …
-conjugated PEI was internalized by caveolae-mediated endocytosis in HEK293T cells, thus …
… effective and targeted cellular uptake of a drug delivery vehicle composed of an integrin-targeting diketopiperazine peptidomimetic and a cell-penetrating peptide
L Feni, S Parente, C Robert, S Gazzola… - Bioconjugate …, 2019 - ACS Publications
… to transport diverse cargos inside almost any kinds of cells. Still, … integrin receptor-mediated
endocytosis was involved, we … of these conjugates with nanoparticle formulations could lead …
endocytosis was involved, we … of these conjugates with nanoparticle formulations could lead …
Studies of cell-penetrating peptides by biophysical methods
M Zorko, Ü Langel - Quarterly Reviews of Biophysics, 2022 - cambridge.org
… On the other part, crotamine conjugated gold nanoparticles … the altered intracellular trafficking
of the peptide after endocytic … Future development of CPP-based drugs greatly depends on …
of the peptide after endocytic … Future development of CPP-based drugs greatly depends on …
Cell-penetrating peptide-mediated nanovaccine delivery
J Jiang - Current Drug Targets, 2021 - ingentaconnect.com
… vaccine delivery systems based on nanotechnology have been … In the case of endocytosis,
the fate of the CPP-cargo … direct covalent conjugation, which facilitates intracellular delivery. …
the fate of the CPP-cargo … direct covalent conjugation, which facilitates intracellular delivery. …
Cell-penetrating peptide-based non-invasive topical delivery systems
… cell selectivity, short half-life in serum, and endocytic sequestration. According to the cellular
uptake mechanisms, extracellular … –polyarginine (R7) conjugate (PsorBan1) for the topical …
uptake mechanisms, extracellular … –polyarginine (R7) conjugate (PsorBan1) for the topical …
Different oligoarginine modifications alter endocytic pathways and subcellular trafficking of polymeric nanoparticles
J Zhou, Y Chau - Biomaterials science, 2016 - pubs.rsc.org
… on the subcellular fate of polymeric nanoparticles, providing … cell-penetrating peptides,
which has exhibited efficient … of polymeric particles, methoxy-PEG-b-PCL was conjugated with …
which has exhibited efficient … of polymeric particles, methoxy-PEG-b-PCL was conjugated with …
[HTML][HTML] Cell penetrating peptides: A concise review with emphasis on biomedical applications
H Derakhshankhah, S Jafari - Biomedicine & Pharmacotherapy, 2018 - Elsevier
… , SiRNA, therapeutic agents, nanoparticles and so on. In this … -mediated endocytosis,
clathrin-mediated endocytosis, clathrin … cells with CPPs conjugated with targeting ligands: 1) Cell …
clathrin-mediated endocytosis, clathrin … cells with CPPs conjugated with targeting ligands: 1) Cell …