Gap junctional intercellular communication as a method to detect and predict carcinogenicity

V Krutovskikh, H Yamasaki - Carcinogenicity, 2021 - taylorfrancis.com
Endogenous and exogenous modulation of gap junctional intercellular communication:
toxicological and pharmacological implications. Life Sci 1993; 53:1-19. Wade MH, Trosko JE, …

Chemical, oncogene and growth regulator modulation of extracellular, intracellular and intercellular communication

JE Trosko, CC Chang, BV Madhukaar… - Cell …, 2018 - taylorfrancis.com
… Therefore, it seems from an evolutionary viewpoint, this important biological function was
designed to be sensitive to a wide variety of endogenous and exogenous extracellular signals, …

Connexin and gap junctions: perspectives from biology to nanotechnology based therapeutics

S Jindal, S Chockalingam, SS Ghosh… - Translational …, 2021 - Elsevier
… The concept of gap junctions and their role in intercellular communication has been known
… biology of connexins in mediating gap junction intercellular communication (GJIC) and their …

A role of connexin 43 on the drug-induced liver, kidney, and gastrointestinal tract toxicity with associated signaling pathways

R Katturajan, SE Prince - Life sciences, 2021 - Elsevier
… through gap junction intercellular communication, regulating … , by excusing endogenous
and exogenous wastes from our … through modulation of intercellular gap junction with targeting …

Application of cell-cell communication assays to problems of developmental toxicology

R Loch-Caruso - In Vitro Methods in Developmental Toxicology, 2019 - taylorfrancis.com
… that gap junctions may mediate the transfer of an endogenous … of junctional communication
by exogenous substances, … are known to increase gap junctional communication, size, …

[PDF][PDF] … of extra-, intra-and gap junctional-intercellular communication in the evolution of multi-cellularity and stem cells: how disrupted cell-cell communication during …

JE Trosko - Int. J. Stem Cell Res. Ther, 2016 - pdfs.semanticscholar.org
… how exposure to endogenous or exogenous agents during … as key factor in the fields of
toxicology, cancer, neurosciences, … turn, modulates gap junctional inter-cellular communication to …

Brain Disorders and Chemical Pollutants: A Gap Junction Link?

M Mesnil, N Defamie, C Naus, D Sarrouilhe - Biomolecules, 2020 - mdpi.com
… While Cx43 is a negative modulator of neuronal … is now largely banned due to its toxicity.
In the environment, lindane … activated by both endogenous and exogenous ligands including …

[PDF][PDF] … Evaluation Of The Effect Of The Natural Product Compound Chaetoglobosin K On Organochlorine-induced Inhibition Of Astroglial Intercellular Communication.

T Sidorova - 2019 - mercer.openrepository.com
… protective effect of ChK on gap junctions in organochlorine-treated … ChK modulate gap
junctional intercellular communication. ix … physiological or toxicological cues. Certain pesticides …

Regulation of gap junction channels and hemichannels by phosphorylation and redox changes: a revision

K Pogoda, P Kameritsch, MA Retamal, JL Vega - BMC cell biology, 2016 - Springer
… as exogenous expression system, but phosphorylation of Cx26 in cells that endogenously
… Gating kinetics of GJ channels can be modulated in a rapid and reversible manner by direct …

Methoxychlor and vinclozolin induce rapid changes in intercellular and intracellular signaling in liver progenitor cells

P Babica, R Zurabian, ER Kumar, R Chopra… - Toxicological …, 2016 - academic.oup.com
… the dysregulation of gap junctional intercellular communication (GJIC… However, there is
increasing evidence that endogenous … altered by EDCs include rapid modulations of ion levels or …