[HTML][HTML] Intra-islet endothelial cell and β-cell crosstalk: Implication for islet cell transplantation

S Narayanan, G Loganathan… - … of transplantation, 2017 - ncbi.nlm.nih.gov
… of different cells within an islet along with intra-islet vessel … and secretion of ET-1 from
bovine ECs[112] and endogenous … of proteins are expressed in pancreatic islets. The major β-…

Modulation of endoglin expression in islets of langerhans by VEGF reveals a novel regulator of islet endothelial cell function

CE Clarkin, M Mahmoud, B Liu, EO Sobamowo… - BMC Research …, 2016 - Springer
… two different populations of endoglin expressing cells in … Native pancreatic islets are
vascularised by a dense network … of VEGF in transplanted mouse islets caused increased …

[HTML][HTML] Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models

Y Aghazadeh, F Poon, F Sarangi, FTM Wong, ST Khan… - Cell Stem Cell, 2021 - cell.com
… umbilical vein endothelial cells (PPEC) before subcutaneous … time because of lack of
endogenous or exogenous insulin (… strategy in different diabetes models, we transplanted PP- and …

Islet regeneration: endogenous and exogenous approaches

FM Docherty, L Sussel - International Journal of Molecular Sciences, 2021 - mdpi.com
… is whole pancreas or pancreatic islet transplantation. Whole … and has achieved long-term
insulin independence and good … that co-transplantation of the sBCs with endothelial cells, …

Hypoxia induction in cultured pancreatic islets enhances endothelial cell morphology and survival while maintaining beta-cell function

KS Sankar, SM Altamentova, JV Rocheleau - PLoS One, 2019 - journals.plos.org
… lead to better outcomes in transplanting this tissue for the … that stimulate endogenous
expression of angiogenic factors. … by flow, thus we believe the main difference between CoCl 2 …

… and opportunities in the islet transplantation microenvironment: a comprehensive summary of inflammatory cytokine, immune cells, and vascular endothelial cells

Q Chen, L Liu, X Zhao, J Liang, S Li - Frontiers in Immunology, 2023 - frontiersin.org
endogenous angiogenic factors produced by transplanted … long-term survival rate of pancreatic
islet transplantation, akin … of the microenvironment on pancreatic islet transplant survival. …

Targeting pancreatic islet PTP1B improves islet graft revascularization and transplant outcomes

H Figueiredo, ALC Figueroa, A Garcia… - Science translational …, 2019 - science.org
Islets from PTP1B −/− mice retained more endothelial cells during in vitro … endogenous
controls for mouse and human islets, respectively. Results were expressed relative to expression

… -rich plasma on the pancreatic islet survival and function, islet transplantation outcome and pancreatic pdx1 and insulin gene expression in streptozotocin-induced …

M Nemati, N Karbalaei, P Mokarram, F Dehghani - Growth Factors, 2020 - Taylor & Francis
Full article: Effects of platelet-rich plasma on the pancreatic islet survival and function, islet
transplantation outcome and pancreatic pdx1 and insulin gene expression in streptozotocin-…

[HTML][HTML] Culturing functional pancreatic islets on α5-laminins and curative transplantation to diabetic mice

K Sigmundsson, JRM Ojala, MK Öhman, AM Österholm… - Matrix Biology, 2018 - Elsevier
… was analyzed using the comparative threshold (Ct) method, using mouse GAPDH as an
endogenous control for RNA load and gene expression. The difference in Ct-values (ΔCt) …

The liver surface is an attractive transplant site for pancreatic islet transplantation

A Inagaki, T Imura, Y Nakamura, K Ohashi… - Journal of Clinical …, 2021 - mdpi.com
… used to detect the luciferase expression. The keratinocyte sheet … Another possible explanation
is that some endogenous … amniotic epithelial cells was applied to islet transplantation to …