Cav3. 1-driven bursting firing in ventromedial hypothalamic neurons exerts dual control of anxiety-like behavior and energy expenditure

J Shao, DS Gao, YH Liu, SP Chen, N Liu, L Zhang… - Molecular …, 2022 - nature.com
… chronic stress affected energy expenditure in stressed mice. … in naïve mice was sufficient
to produce a similar response in … indicated that enhancement of burst firing induced by local …

Brain insulin signalling in metabolic homeostasis and disease

T Scherer, K Sakamoto, C Buettner - Nature Reviews Endocrinology, 2021 - nature.com
Noradrenaline is released from sympathetic fibres and … basal hypothalamus (MBH) acutely
restrains lipolysis in rats as … (NIRKO)) of mice results in increased lipolytic rates in the fasted …

[PDF][PDF] A hypothalamic phosphatase switch coordinates energy expenditure with feeding

GT Dodd, ZB Andrews, SE Simonds, NJ Michael… - Cell metabolism, 2017 - cell.com
… b cells is increased in response to a rise in blood glucose, activate … the fasting-induced
increase in hypothalamic TCPTP). … AgRPTC mice after 3 weeks of high-fat feeding and measured …

[PDF][PDF] The sense of smell impacts metabolic health and obesity

CE Riera, E Tsaousidou, J Halloran, P Follett, O Hahn… - Cell metabolism, 2017 - cell.com
… In mice and other rodents, the hypothalamus receives … levels of the catecholamine
noradrenaline, a major agonist of b-adrenergic receptors, in OMPDTR mice consistent with …

Nighttime administration of nicotine improves hepatic glucose metabolism via the hypothalamic orexin system in mice

H Tsuneki, T Nagata, M Fujita, K Kon, N Wu… - …, 2016 - academic.oup.com
… .05) were induced in Orexin −/− mice by high-fat feeding (at ZT 14)… effects of nicotine on blood
glucose levels were moderate, … improved hepatic glucose metabolism via the hypothalamic

Central and peripheral inflammation link metabolic syndrome and major depressive disorder

KL Chan, F Cathomas, SJ Russo - Physiology, 2019 - journals.physiology.org
… insulin to regulate blood glucose levels (53). Since then, the … In mice, high-fat diets induce
hypothalamic and hippocampal … high-fat feeding in the Flinders sensitive line genetic rat model …

Regulation of substrate utilization and adiposity by Agrp neurons

JP Cavalcanti-de-Albuquerque, J Bober… - Nature …, 2019 - nature.com
… Here, we found that activation of hypothalamic Agrp neurons … Norepinephrine release and
binding to adrenergic receptors … high-fat feeding were resistant to diet-induced obesity with …

Glucose activates vagal control of hyperglycemia and inflammation in fasted mice

B Joseph, G Shimojo, Z Li, MR Thompson-Bonilla… - Scientific reports, 2019 - nature.com
… /fed mice had statistically similar blood glucose levels before … catecholamines: dopamine,
norepinephrine, and epinephrine… (AgRP) neurons in the hypothalamic arcuate nucleus and the …

Antipsychotics and glucose metabolism: how brain and body collide

C Kowalchuk, LN Castellani… - … Journal of …, 2019 - journals.physiology.org
… -fat feeding, owing in part to increased hepatic glucose output (… in epinephrine and
norepinephrine levels, glucagon secretion, … increased activation of hypothalamic AMPK in rodents

Innate obesity, revealed by selection markers, confers significant imprint of hypothalamic genes controlling energy expenditure

BA Henry - Neuroendocrinology, 2017 - karger.com
… diet, DIO rats have elevated body weights and increased … show a greater reduction in 24-h
urine noradrenaline levels … ARC in DIO rats and mice in response to highfat feeding, such as …