Tendon-derived extracellular matrix enhances transforming growth factor-β3-induced tenogenic differentiation of human adipose-derived stem cells

G Yang, BB Rothrauff, H Lin, S Yu… - Tissue Engineering Part …, 2017 - liebertpub.com
… We found that (1) tECM enhanced TGF-β3-induced tenogenesis of hASCs in both plate
and scaffold culture, and (2) tECM favorably modulated matrix deposition and organization by …

[HTML][HTML] Tenogenic induction of human adipose-derived stem cells by soluble tendon extracellular matrix: composition and transcriptomic analyses

Y Rao, C Zhu, HC Suen, S Huang, J Liao… - Stem Cell Research & …, 2022 - Springer
tendon-derived extracellular matrix (tECM) that exhibits strong pro-tenogenic bioactivity on
human adipose-derived stem cells … the enhanced proliferation and tenogenic differentiation of …

Extracorporeal shock waves trigger tenogenic differentiation of human adipose-derived stem cells

L Rinella, F Marano, L Paletto… - Connective Tissue …, 2018 - Taylor & Francis
tenogenic medium. Quantitative real-time PCR was used to check the mRNA expression
levels of tenogenic transcription factors, extracellular … We observed an enhanced expression of …

Tenogenically differentiated adipose-derived stem cells are effective in Achilles tendon repair in vivo

JB Norelli, DP Plaza, DN Stal… - Journal of Tissue …, 2018 - journals.sagepub.com
Tendon-derived stem cells (TDSCs) have also been … phosphate crystals found in osteocyte
extracellular matrix (ECM). The … We speculate that the improvement in tissue repair may be …

Tendonderived extracellular matrix induces mesenchymal stem cell tenogenesis via an integrin/transforming growth factor‐β crosstalk‐mediated mechanism

D Wang, CCM Pun, S Huang, TCM Tang… - The FASEB …, 2020 - Wiley Online Library
… of enhancing transforming growth factor-β (TGF-β) mediated tenogenesis in human
adipose-derived stem cells (… of tECM-driven hASC tenogenic differentiation in vitro, focusing on the …

Harnessing biochemical and structural cues for tenogenic differentiation of adipose derived stem cells (ADSCs) and development of an in vitro tissue interface …

SKM Perikamana, J Lee, T Ahmad, EM Kim, H Byun… - Biomaterials, 2018 - Elsevier
… greatly enhanced the proliferation and tenogenic differentiation of … stem cells or the limited
availability of tendon derived stem … The cellular and extracellular matrix at the insertion site is …

Tendon tissue engineering: Current progress towards an optimized tenogenic differentiation protocol for human stem cells

I Donderwinkel, RS Tuan, NR Cameron, JE Frith - Acta Biomaterialia, 2022 - Elsevier
… further be improved by use of extracellular vesicles (EVs). Rat … of human adipose stem cells
(hASCs) with tendon-derived … its pro-tenogenic activity was further enhanced by addition of …

[HTML][HTML] 3D bioprinting of human adipose-derived stem cells and their tenogenic differentiation in clinical-grade medium

D Stanco, M Boffito, A Bogni, L Puricelli… - International journal of …, 2020 - mdpi.com
… and maintenance of tendon extracellular matrix homeostasis; … of tendon-derived stem cells
(TDSCs) proliferation and … FAK and ERK1/2, was enhanced in TDSCs cultured on stiff gelatin …

Tenogenesis of bone marrow-, adipose-, and tendon-derived stem cells in a dynamic bioreactor

DW Youngstrom, JE LaDow… - Connective tissue research, 2016 - Taylor & Francis
… TNs are hypocellular tissues composed of aligned, hierarchically organized extracellular
matrix (… There is also concern that immunogenicity may be enhanced following differentiation (…

Tenocyte-imprinted substrate: A topography-based inducer for tenogenic differentiation in adipose tissue-derived mesenchymal stem cells

SMA Haramshahi, S Bonakdar… - Biomedical …, 2020 - iopscience.iop.org
… a sheet capable of enhancing the expression of tenocyte … extracellular matrix (ECM)) production
capacity in tenogenic … and only using tendon-derived mesenchymal stem cells [86]. The …