… of these diseases and how epigenetic changes can affect the severity of this … SENP1 leads
to an accumulation of HDAC4 on the MMP-1 promoter and decrease of MMP-1 expression…

… RA-FLSs was characterized by high expression levels of SUMO-1 and MMP-1, and low
expression levels of SENP1… the up-regulated SENP5 or SENP7, or down-regulated SENP1, they …

… are also considered epigenetic regulatory mechanisms. … of MMP-1 and SUMO-1 and also
low expression of SENP1 (… of SENP1 showed a decreased acetylation of H4 in the MMP-1 …

… abnormal expression of non-coding RNAs associated with RA … Epigenetic mechanisms
regulate chromatin structure and … marks as well as the abundance of MMP-1, MMP-3, MMP-9, …

… In summary, MMP-1 and 3 expression in TB is regulated by HDAC and HAT activity. MMP-1
upregulation, as a result of epigenetic control, has the potential to drive tissue damage in the …

… The term “epigenetics” describes mechanisms that regulate … In rheumatoid arthritis (RA),
epigenetic alterations have been … to increased expression of MMP-1 in RA synovial fibroblasts […

… Epigenetic regulators of histone tail modifications play a role in … We have found that RA
synovial HDAC5 expression … in the RA acetylome, and their regulation and recognition by …

… Epigenetic mechanisms alter the accessibility of DNA by … that environmental modifications
of this enzymes regulate … acetylację w regionie promotorowym MMP-1 i zwiększa ekspresję …

… SUMOylation is also implicated in the epigenetic regulation of osteogenesis. In human dental
… SENP1 attenuates rheumatoid arthritis by suppressing MMP1 expression. SUMOylation of …

… SUMOylation is also implicated in the epigenetic regulation of … Rheumatoid arthritis (RA) is
a chronic systemic, inflammatory … in RA comes from the finding that expression of the SENP1 …