Epigenetic regulation of B cell fate and function during an immune response

Y Zhang, KL Good‐Jacobson - Immunological Reviews, 2019 - Wiley Online Library
epigenetic modifications underpinning B cell fate and function during an immune response.
… Furthermore, methylation status of peripheral blood memory B cell subsets separated based …

Epigenetic regulation in B-cell maturation and its dysregulation in autoimmunity

H Wu, Y Deng, Y Feng, D Long, K Ma, X Wang… - Cellular & molecular …, 2018 - nature.com
… In the peripheral lymphoid system, mature B cells are … T cells for differentiating into either
memory B cells or antibody-… RNAs in B-cell differentiation and antibody response has mainly …

Epigenetic control of B cell development and B-cell-related immune disorders

Y Bao, X Cao - Clinical reviews in allergy & immunology, 2016 - Springer
Peripheral B cell development … of B-cell-related autoimmunity and malignancies. Until now,
we only have small glimpses into the nature of epigenetic regulation on B cell development

Epigenetic programming underpins B cell dysfunction in human SLE

CD Scharer, EL Blalock, T Mi, BG Barwick… - Nature …, 2019 - nature.com
Peripheral B cells can be divided into subtypes that … epigenetic feature of B cell differentiation
is the targeted and progressive global hypomethylation that occurs as B cells differentiate

Epigenetic regulation of B cells and its role in autoimmune pathogenesis

F Xiao, K Rui, X Shi, H Wu, X Cai, KO Lui… - Cellular & Molecular …, 2022 - nature.com
… , we discuss epigenetic modifications in different functional B-cell subsets … antibody secretion,
and cytokine production, under different conditions. Maturation and activation of peripheral

B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids

HN Sanchez, JB Moroney, H Gan, T Shen, JL Im… - Nature …, 2020 - nature.com
… promote thymic production of FOXP3 + Tregs and peripheral … possibly B-cell-intrinsic,
modulation of the antibody response, … IgG3 and IgG2b) antibody response, with a significantly …

[图书][B] Epigenetics of B Cells and Antibody Responses

P Casali - 2016 - books.google.com
… It is now clear that epigenetic changes regulate B cell development. By acting in concert …
antibody response; such epigenetic changes underpin the maturation of the antibody response

EZH2 represses the B cell transcriptional program and regulates antibody-secreting cell metabolism and antibody production

M Guo, MJ Price, DG Patterson, BG Barwick… - The Journal of …, 2018 - journals.aai.org
Epigenetic remodeling is required during B cell differentiation. However, little is known about
the direct functions of epigenetic … (26, 51); however, it is dispensable for peripheral B cell

Regulation of germinal center responses, memory B cells and plasma cell formation—an update

LM Corcoran, DM Tarlinton - Current opinion in immunology, 2016 - Elsevier
… a contemporary model of B cell differentiation, highlighting … diffuse large B cell lymphomas),
Phf19 (an epigenetic regulator; … almost infinite versatility of the antibody response is likely the …

Regulatory mechanisms of B cell responses and the implication in B cell-related diseases

DY Tsai, KH Hung, CW Chang, KI Lin - Journal of biomedical science, 2019 - Springer
… regulation and epigenetic regulation, on B cell activation, and … Loss of IRF4 leads to impaired
antibody production [27]. XBP-1 … In this study, human peripheral blood B cells were treated …