Caffeine protects against anticonvulsant-induced neurotoxicity in the developing rat brain

S Endesfelder, U Weichelt, C Schiller, M Sifringer… - Neurotoxicity …, 2017 - Springer
… of cerebral palsy in human infants treated with caffeine. We hypothesized that caffeine
may counteract the proapoptotic effects of phenobarbital in newborn rats. Postnatal day 4 (P4) …

Caffeine restores background EEG activity independent of infarct reduction after neonatal hypoxic ischemic brain injury

H Sun, F Gonzalez, PS McQuillen - Developmental neuroscience, 2020 - karger.com
brain activity after injury to further understand caffeine neuroprotection. Rat dams received
caffeine … This method was used for all groups regardless of caffeine treatment, and hypoxia

[PDF][PDF] Hippocampal Oxygen Dynamics During and Following Febrile Seizures

S Harris - 2021 - prism.ucalgary.ca
Caffeine had a proconvulsant effect and resulted in less oxygen fluctuations in the hippocampus
Regarding possible postictal hypoxia or hyperoxia in neonatal rats with febrile seizures, …

The effect of prenatal and postnatal caffeine exposure on pentylentetrazole induced seizures in the non-epileptic and epileptic offsprings

M Yavuz, N Albayrak, M Özgür, MGİ Oğlu, S Cavdar… - Neuroscience …, 2019 - Elsevier
… The location of the SSCx, Rt, VB, CM and LGN were identified according to the rat brain
did not induce c-Fos protein expression normally evoked by hypoxia in rats [49]. In our study …

Caffeine and seizures: A systematic review and quantitative analysis

RR van Koert, PR Bauer, I Schuitema, JW Sander… - Epilepsy & Behavior, 2018 - Elsevier
caffeine and epileptic phenomena or AEDs in vitro, in animal studies, or in humans were
included. Studies describing the effects of caffeineCaffeine influences brain excitability and …

[HTML][HTML] Recording of hippocampal activity on the effect of convulsant doses of caffeine

L Eiró-Quirino, FK Yoshino, GC de Amorim… - Biomedicine & …, 2024 - Elsevier
… In addition, epileptogenic alterations during the … - hypoxia and consequently death, since
responses at brain level depend intrinsically on the supply of oxygen by the blood, but during

Neonatal seizures and purinergic signalling

A Menéndez Méndez, J Smith, T Engel - International journal of molecular …, 2020 - mdpi.com
… followed by a brief period of hypoxia in neonatal rats (P7). This … neurogenesis in neonatal
rats [287], possibly due to caffeine’… role in epileptogenesis following an insult to the infant brain. …

… oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and …

M Crespo, DA León-Navarro, M Martin - European journal of pharmacology, 2018 - Elsevier
caffeine consumption during gestation and lactation can exert protective effects on developing
brain … maternal caffeine consumption during gestation and lactation exhibited protective …

Early-life exposure to caffeine affects the construction and activity of cortical networks in mice

W Fazeli, S Zappettini, SL Marguet, J Grendel… - Experimental …, 2017 - Elsevier
… , alters brain development. We hypothesized that maternal caffeine ingestion during pregnancy
… detrimental effects of developmental caffeine exposure on mouse brain development. …

[图书][B] Caffeine Combined with Sedative/Anesthetic Drugs Used in Neonatal Medicine and Apoptotic Neurotoxicity in Developing Mouse Brain

OH Cabrera - 2016 - search.proquest.com
… by episodes of hypoxia and bradycardia that occur sporadically or chronically during
extended … fusion in the developing rat brain. Anesthesiology, 118(5), 1086–1097. doi:10.1097/ALN.…