[HTML][HTML] Oxymatrine induces cell cycle arrest and apoptosis and suppresses the invasion of human glioblastoma cells through the EGFR/PI3K/Akt/mTOR signaling …

Z Dai, L Wang, X Wang, B Zhao, W Zhao… - Oncology …, 2018 - spandidos-publications.com
cells with erlotinib, an inhibitor of EGFR, in the absence or presence of OM for 48 h. The results
indicated that in the presence of both erlotinib … and increases the risk of tumor recurrence (…

PLAGL2‐EGFR‐HIF‐1/2α signaling loop promotes HCC progression and erlotinib insensitivity

W Hu, S Zheng, H Guo, B Dai, J Ni, Y Shi, H Bian… - …, 2021 - Wiley Online Library
… common type of liver cancer worldwide. It is estimated to be … can also induce cell cycle
regulation and apoptosis through … cells and neuroblastoma Neuroa2a cells led to an increase in …

Inhibition of cyclin E1 sensitizes hepatocellular carcinoma cells to regorafenib by mcl-1 suppression

J Xu, F Huang, Z Yao, C Jia, Z Xiong, H Liang… - Cell Communication and …, 2019 - Springer
enhanced expression of cyclin E1 after transfection compromised apoptosis in HCC cells
induced … The suppression of cell cycle regulator levels by sorafenib may enhance its antitumor …

Titanium oxide nanoparticles improve the chemotherapeutic action of erlotinib in liver cancer cells

SE Abdel-Ghany, E El-Sayed, N Ashraf… - Current Cancer …, 2020 - ingentaconnect.com
… proved to be a reliable approach to enhance drug release and bioavailability. Our results …
lotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances

Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells

TW Chung, SC Lin, JH Su, YK Chen, CC Lin… - … and alternative medicine, 2017 - Springer
… and subsequently induced cell cycle G2/M arrest associated … (p53-dependent) but also to
increase the protein levels of … enzyme inhibitor, Erlotinib, was applied for treatment of advanced …

2-Methoxyestradiol synergizes with Erlotinib to suppress hepatocellular carcinoma by disrupting the PLAGL2-EGFR-HIF-1/2α signaling loop

S Zheng, J Ni, Y Li, M Lu, Y Yao, H Guo, M Jiao… - Pharmacological …, 2021 - Elsevier
… into cancer chemotherapy. However, the therapeutic effects of erlotinib in hepatocellular
carcinoma (… 2ME2 promotes tumor cells apoptosis and inhibits tumor cells proliferative in several …

… enhances erlotinib-induced cytotoxicity via AKT inactivation and excision repair cross-complementary 1 (ERCC1) down-regulation in human lung cancer cells

JC Chen, JC Ko, TC Yen, TY Chen, YC Lin… - Toxicology …, 2019 - academic.oup.com
… ) in hepatocellular carcinoma cells. Capsaicin enhances apoptosis and restricts benzo(a)pyrene
induced … effects of a combined treatment using erlotinib and capsaicin on NSCLC cells. …

[HTML][HTML] β-elemene enhances the antitumor activity of erlotinib by inducing apoptosis through AMPK and MAPK pathways in TKI-resistant H1975 lung cancer cells

J Wang, C Xu, Y Chen, L Shao, T Li, X Fan, L Yu… - … of Cancer, 2021 - ncbi.nlm.nih.gov
Cell cycle arrest can save time for DNA repair. On the other hand, if the intracellular damage
… of tumors including lung cancer, liver cancer, digestive tract cancer, and bladder cancer, etc.…

Synergistic activity of vorinostat combined with gefitinib but not with sorafenib in mutant KRAS human non-small cell lung cancers and hepatocarcinoma

V Jeannot, B Busser, L Vanwonterghem… - OncoTargets and …, 2016 - Taylor & Francis
… Gefitinib and erlotinib are epidermal growth factor receptor (… a survival benefit for advanced
hepatocellular carcinoma (HCC). … failed to enhance apoptosis in both NSCLC and HCC cells. …

[HTML][HTML] … activity of aspirin and erlotinib: Inhibition of p38 enhanced aspirin plus erlotinibinduced suppression of metastasis and promoted cancer cell apoptosis

X Hu, LW Wu, X Weng, NM Lin… - Oncology …, 2018 - spandidos-publications.com
… plus erlotinib could increase the expression of E-cadherin; thus, we hypothesized that aspirin
plus erlotinib may inhibit EMT and cancer metastasis. EMT enables cancer cell migration …