… neurotrophin system by estrogen in the basal forebrain. Studies investigating the impact of
estrogens … In one such example, long-term estrogen deprivation experiments have shown that …

… The projections are negatively impacted by aging, as well as by Alzheimer’s and Parkinson’…
by loss of estrogens (eg, menopause) and are positively impacted by estrogen replacement …

… , and the potential implications for the development of … dysfunction seen in Alzheimer's
disease and normal aging. This … the trophic factor for basal forebrain cholinergic neurons [107]. …

… Estrogen and basal forebrain cholinergic neurons: implications for brain aging and
Alzheimer's diseaserelated cognitive decline. Horm Behav 34: 98-111 (1998). [53] Schneider LS, …

… In Alzheimer’s disease (AD), there is a loss in cholinergic innervation targets of basal forebrain
… we examined the effect of estren on Aβ 1–42 -induced cholinergic damage in BFC in vivo. …

… aging as a major risk factor. Early and progressive degeneration of basal forebrain cholinergic
neurons (… An aging-relevant cell model of BFCNs will critically help understand AD and …

… aging and neurodegenerative diseases, particularly AD. The interaction … estrogen and the
basal forebrain cholinergic system … : implications for cognitive decline in aging and Alzheimer’s …

… in basal forebrain (cholinergic function) and Aβ in elderly … As estradiol modulates cholinergic
neurons in the brain, 17, … whether estradiol treatment in OVX animals impacts the effect of …

… basal forebrain (BF) is associated to the cognitive decline of … The effect of NGF on cholinergic
neuronal differentiation was … expressed estrogen receptors and responded to 17β-estradiol …

… risk of neurocognitive decline and Alzheimer's disease (AD) … However, similar to estrogen
replacement's effect in … ” Estrogen's impact on the cholinergic system may act both locally in the …