… Moreover, I tested the effect of manipulating cholinergic systems and the effect of … basal
forebrain cholinergic projections and estrogen effects on performance that impact brain aging …

… standard of care for the symptomatic treatment of Alzheimer's disease (AD) and show significant
… A comprehensive understanding of cerebral and retinal cholinergic system dysfunctions …

… cognitive disruption (such as Alzheimer’s disease (AD) and … effect of the contraceptive pill
on verbal abilities (potentially related to the estrogen component of the pill) as well as an effect …

… by the cholinergic phenotype in the basal forebrain beta-amyloid … an increase in DCX+
neurons with no effect of exercise. However… Temporal and bidirectional influences of estradiol on …

… average age of menopause onset occurs at 51, the estrogen … study, re-assessed how age
of initiation modulated AD risk. … that estrogen supplementation did have a protective effect, but …

… Alzheimer’s disease (AD) is the cause of significant … effect of estrogens as neuroprotectors
in neurodegenerative diseases during menopause showed contradictory facts. While aging …

… +IR cholinergic neurons in the female basal forebrain relative to males (Main effect of Sex:
F[1… We report that AIE decreased ChAT+ BFCNs in the adult basal forebrain, an effect that was …

… The results of the study suggested that the activation of GPR30 besides classical estrogen
… , the effect of brain GPR30 activation on memory function in mouse models of Alzheimer's …

… cholinergic innervations from the basal forebrain to the hippocampus has been implicated in
Alzheimer’… , a single dose of estradiol restored the cholinergic fibers loss—an effect that was …

… birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their
… of a subset of neurons, known as basal forebrain cholinergic neurons (BFCNs), in DS and …